OPTIMAL FOCAL TRANSCRANIAL MAGNETIC ACTIVATION OF THE HUMAN MOTOR CORTEX - EFFECTS OF COIL ORIENTATION, SHAPE OF THE INDUCED CURRENT PULSE, AND STIMULUS-INTENSITY

被引：501

作者：

BRASILNETO, JP

COHEN, LG

PANIZZA, M

NILSSON, J

ROTH, BJ

HALLETT, M

机构：

[1] NINCDS,MED NEUROL BRANCH,HUMAN MOTOR CONTROL SECT,HUMAN CORT PHYSIOL UNIT,BLDG 10,BETHESDA,MD 20892

[2] NATL CTR RES RESOURCES,BIOMED ENGN & INSTRUMENTAT PROGRAM,BETHESDA,MD

来源：

JOURNAL OF CLINICAL NEUROPHYSIOLOGY | 1992年 / 9卷 / 01期

关键词：

MAGNETIC STIMULATION; MOTOR CORTEX; MAGNETIC COIL; MOTOR EVOKED POTENTIALS; BRAIN MAPPING; CORTICAL STIMULATION;

D O I：

10.1097/00004691-199201000-00014

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied the effects of coil orientation, stimulus intensity, and shape of the induced current pulse on the amplitudes of motor evoked potentials in the left abductor pollicis brevis of 10 normal adults who had transcranial magnetic stimulation. The optimal direction of currents induced in the brain is approximately perpendicular to the central sulcus, flowing diagonally from back to front. The most effective coil orientation depends on the shape of the induced current pulse and, when the first and second phases of the pulse are of similar size, also on the intensity of stimulation. Optimal mapping of the human motor cortex with magnetic stimulation requires knowledge of the influences of all these factors.

引用

页码：132 / 136

页数：5

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