ACCEPTOR ANALOGS AS POTENTIAL INHIBITORS OF BOVINE BETA-1,4-GALACTOSYL TRANSFERASE

被引：12

作者：

FIELD, RA ^{[1
]}

NEVILLE, DCA ^{[1
]}

SMITH, RW ^{[1
]}

FERGUSON, MAJ ^{[1
]}

机构：

[1] UNIV DUNDEE,DEPT BIOCHEM,DUNDEE DD1 4HN,SCOTLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 03期

关键词：

D O I：

10.1016/0960-894X(94)80002-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of 4- and B-substituted derivatives of benzyl N-acetyl-beta-(D) under bar-glucosaminide were prepared and assessed as inhibitors of bovine beta-1,4-galactosyl transferase. Of the azido, amino, and acetamido compounds tested, only the 4-amino compound (2) produced significant inhibition of this enzyme.

引用

页码：391 / 394

页数：4

共 28 条

[1]

BERLINER LJ, 1984, MOL CELL BIOCHEM, V62, P37, DOI 10.1007/BF00230075

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