CHOOSING A CELL FATE - A VIEW FROM THE NOTCH LOCUS

被引：194

作者：

ARTAVANISTSAKONAS, S

SIMPSON, P

机构：

[1] YALE UNIV,HOWARD HUGHES MED INST,DEPT BIOL,NEW HAVEN,CT 06520

[2] FAC MED STRASBOURG,INSERM,CNRS,UNITE BIOL MOLEC GEN GENET 184,GENET MOLEC LAB,F-67085 STRASBOURG,FRANCE

来源：

TRENDS IN GENETICS | 1991年 / 7卷 / 11-12期

关键词：

D O I：

10.1016/0168-9525(91)90264-Q

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

During the development of Drosophila melanogaster, individual cells must make choices between a restricted set of possible fates in order to give rise to spatial patterns composed of different types of differentiated cells. The Notch locus appears to play a central and general role in the regulative events that control the local architecture of the final cellular pattern in several tissues, among them being the central and peripheral nervous systems.

引用

页码：403 / 408

页数：6

共 45 条

[1]

AKAM M, 1987, DEVELOPMENT, V101, P1

[2]

ARTAVANISTSAKONAS S, 1991, ANNU REV CELL BIOL, V7, P427

[3] THE MOLECULAR-BIOLOGY OF THE NOTCH LOCUS AND THE FINE TUNING OF DIFFERENTIATION IN DROSOPHILA [J].