THE MECHANISM OF ACTIVATION OF 4-HYDROXYCYCLOPHOSPHAMIDE

[1] INSITU PREPARATION AND FATE OF CIS-4-HYDROXYCYCLOPHOSPHAMIDE AND ALDOPHOSPHAMIDE - H-1 AND P-31 NMR EVIDENCE FOR EQUILIBRATION OF CIS-4--HYDROXYCYCLOPHOSPHAMIDE AND TRANS-4-HYDROXYCYCLOPHOSPHAMIDE WITH ALDOPHOSPHAMIDE AND ITS HYDRATE IN AQUEOUS-SOLUTION [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (04) : 490 - 494

[2] BASE-CATALYZED-HYDROLYSIS OF 4-HYDROPEROXYCYCLOPHOSPHAMIDE - EVIDENCE FOR IMINOCYCLOPHOSPHAMIDE AS AN INTERMEDIATE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (04) : 485 - 490

[3] CACECI MS, 1984, BYTE, V9, P340

[4] FENSELAU C, 1982, DRUG METAB DISPOS, V10, P636

[5] Friedman O.M., 1979, ADV CANCER CHEMOTHER, V1, P143

[6] SYNTHESIS AND ABSOLUTE-CONFIGURATION OF OPTICALLY-ACTIVE FORMS OF 2-[BIS(2-CHLOROETHYL)AMINO]-4-METHYLTETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE(4-METHYLCYCLOPHOSPHAMIDE) [J]. JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (09) : 1650 - 1652

[7] KOVACH JS, 1984, INVEST NEW DRUG, V2, P155

[8] ACTIVATION MECHANISMS OF MAFOSFAMIDE AND THE ROLE OF THIOLS IN CYCLOPHOSPHAMIDE METABOLISM [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) : 395 - 399

[9] LOW JE, 1983, CANCER RES, V43, P5815

[10] PETER G, 1976, CANCER TREAT REP, V60, P429

[1] INSITU PREPARATION AND FATE OF CIS-4-HYDROXYCYCLOPHOSPHAMIDE AND ALDOPHOSPHAMIDE - H-1 AND P-31 NMR EVIDENCE FOR EQUILIBRATION OF CIS-4--HYDROXYCYCLOPHOSPHAMIDE AND TRANS-4-HYDROXYCYCLOPHOSPHAMIDE WITH ALDOPHOSPHAMIDE AND ITS HYDRATE IN AQUEOUS-SOLUTION [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (04) : 490 - 494

[2] BASE-CATALYZED-HYDROLYSIS OF 4-HYDROPEROXYCYCLOPHOSPHAMIDE - EVIDENCE FOR IMINOCYCLOPHOSPHAMIDE AS AN INTERMEDIATE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (04) : 485 - 490

[3] CACECI MS, 1984, BYTE, V9, P340

[4] FENSELAU C, 1982, DRUG METAB DISPOS, V10, P636

[5] Friedman O.M., 1979, ADV CANCER CHEMOTHER, V1, P143

[6] SYNTHESIS AND ABSOLUTE-CONFIGURATION OF OPTICALLY-ACTIVE FORMS OF 2-[BIS(2-CHLOROETHYL)AMINO]-4-METHYLTETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE(4-METHYLCYCLOPHOSPHAMIDE) [J]. JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (09) : 1650 - 1652

[7] KOVACH JS, 1984, INVEST NEW DRUG, V2, P155

[8] ACTIVATION MECHANISMS OF MAFOSFAMIDE AND THE ROLE OF THIOLS IN CYCLOPHOSPHAMIDE METABOLISM [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) : 395 - 399

[9] LOW JE, 1983, CANCER RES, V43, P5815

[10] PETER G, 1976, CANCER TREAT REP, V60, P429