BIOSYNTHESIS OF FURAQUINOCIN-A AND FURAQUINOCIN-B

被引：59

作者：

FUNAYAMA, S

ISHIBASHI, M

KOMIYAMA, K

OMURA, S

机构：

[1] KITASATO UNIV,KITASATO INST,5-9-1 SHIROKANE,MINATO KU,TOKYO 108,JAPAN

[2] KITASATO UNIV,SCH PHARMACEUT SCI,TOKYO 108,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 04期

关键词：

D O I：

10.1021/jo00291a003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The biosynthetic pathway to furaquinocins was investigated by means of incorporation experiments with [l-13C]acetate, [l,2-13C2] acetate, and [methyl-12C]-L-methionine. Furaquinocins are derived from a penta-ketide, two mevalonates, and two C1 units from L-methionine. © 1990, American Chemical Society. All rights reserved.

引用

收藏

页码：1132 / 1133

页数：2

相关论文

共 11 条

[1] C-13 AND H-2 LABELING STUDIES ON THE BIOSYNTHESIS OF SCYTALONE IN PHIALAPHORA-LAGERBERGII [J].

BARDSHIRI, E ;

SIMPSON, TJ .

TETRAHEDRON, 1983, 39 (21) :3539-3542

[2] NATURAL ABUNDANCE C-13-C-13 COUPLING OBSERVED VIA DOUBLE-QUANTUM COHERENCE [J].

BAX, A ;

FREEMAN, R ;

KEMPSELL, SP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (14) :4849-4851

[3] STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESIS - BIOSYNTHESIS OF PENTALENOLACTONE FROM [U-C-13(6)]GLUCOSE AND [6-H-2(2)]GLUCOSE [J].

CANE, DE ;

ROSSI, T ;

TILLMAN, AM ;

PACHLATKO, JP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (07) :1838-1843

[4] STRUCTURE OF PHENAZINOMYCIN, A NOVEL ANTITUMOR ANTIBIOTIC [J].

FUNAYAMA, S ;

EDA, S ;

KOMIYAMA, K ;

OMURA, S ;

TOKUNAGA, T .

TETRAHEDRON LETTERS, 1989, 30 (24) :3151-3154

[5]

FUNAYAMA S, IN PRESS TETRAHEDRON

[6] BIOSYNTHETIC-STUDIES OF TERPENTECIN [J].

ISSHIKI, K ;

TAMAMURA, T ;

SAWA, T ;

NAGANAWA, H ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1986, 39 (11) :1634-1635

[7]

KOMIYAMA K, IN PRESS J ANTIBIOT

[8]

SAITOH T, 1975, TETRAHEDRON LETT, P4461, DOI 10.1016/S0040-4039(00)91092-X

[9]

SANKAWA U, 1977, TETRAHEDRON LETT, P483

[10]

SETO H, 1977, TETRAHEDRON LETT, P487