STUDIES WITH RADIOACTIVE IODINE LABELED ESTROGENS AS PROSTATE SCANNING AGENTS

被引：32
作者：
GHANADIAN, R
WATERS, SL
THAKUR, ML
CHISHOLM, GD
机构：
[1] ROY POSTGRAD MED SCH,UROL UNIT,PROSTATE RES LAB,LONDON W12 0HS,ENGLAND
[2] HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,DUCANE RD,LONDON W12 0HS,ENGLAND
来源：
INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1975年 / 26卷 / 6-7期
关键词：
BIOMEDICAL ENGINEERING - Diagnosis - ISOTOPES - Radioactivity;
D O I：
10.1016/0020-708X(75)90036-8
中图分类号：
TL [原子能技术]; O571 [原子核物理学];
学科分类号：
0827 ; 082701 ;
摘要：
A method for the preparation of high specific activity iodo-oestrogens is described together with the results of distribution studies of **1**3**1I iodo-oestradiol in the rat. It was concluded that the uptake of the radioactivity by the prostate was insufficient for localization studies by external detectors, and that in vivo, 2, iodo and 2,4 di-iodo-oestradiol released iodine, as suggested by the deposition of radioactivity into the thyroid. Data are presented in graphical and tabular form.
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页码：343 / &
相关论文
共 22 条
[1]  
ALBERT S, 1949, J BIOL CHEM, V177, P247
[2]   GAMMA COUNTING OF I-125 USING A METAL-LOADED LIQUID SCINTILLATOR [J].
ASHCROFT, J .
ANALYTICAL BIOCHEMISTRY, 1970, 37 (02) :268-&
[3]  
BLAIR RJ, 1971, J NUCL MED, V12, P176
[4]  
CHISHOLM GD, 1974, J NUCL MED, V15
[5]  
CHISHOLM GD, 1970, ASPECTS AETIOLOGY BI
[6]  
COUNSELL RE, COMMUNICATION
[7]   EFFECT OF STEROID HORMONES OVARIECTOMY ESTROGEN PRETREATMENT SEX AND IMMATURITY ON DISTRIBUTION OF 3H-ESTRADIOL [J].
EISENFELD, AJ ;
AXELROD, J .
ENDOCRINOLOGY, 1966, 79 (01) :38-+
[8]   PREPARATION OF I-131-LABELED META-IODOHIPPURIC ACID AND ITS BEHAVIOR IN KIDNEY FUNCTION STUDIES COMPARED TO ORTHO-IODOHIPPURIC ACID [J].
ELIAS, H ;
ARNOLD, C ;
KLOSS, G .
INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1973, 24 (08) :463-469
[9]   ELECTRON CAPTURE RESPONSE FOLLOWING GAS LIQUID CHROMATOGRAPHY OF VARIOUS HALOGENATED DERIVATIVES OF 17BETA-OESTRADIOL AND OESTRONE [J].
EXLEY, D ;
DUTTON, A .
STEROIDS, 1969, 14 (05) :575-&
[10]  
GHANADIAN R, 1972, STEROIDS LIPID RES, V3, P363
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