Corticosteroids for the treatment of non-arteritic anterior ischemic optic neuropathy

被引：0

作者：

Al-Zubidi, Nagham ^{[1
,2
,3
,4
]}

McGlynn, Margaret M. ^{[5
]}

Yalamanchili, Sushma ^{[1
,2
,3
,4
]}

Lee, Andrew G. ^{[1
,2
,3
,4
,6
,7
,8
,9
]}

机构：

[1] Houston Methodist Hosp, Dept Ophthalmol, Houston, TX 77030 USA

[2] Weill Cornell Med Coll, Dept Ophthalmol, Houston, TX USA

[3] Weill Cornell Med Coll, Dept Neurol, Houston, TX USA

[4] Weill Cornell Med Coll, Dept Neurosurg, Houston, TX USA

[5] Weill Cornell Med Coll, New York, NY 10021 USA

[6] Baylor Coll Med, Dept Ophthalmol, Houston, TX 77030 USA

[7] Univ Iowa Hosp & Clin, Dept Ophthalmol, Iowa City, IA 52242 USA

[8] Univ Texas Med Branch, Dept Ophthalmol, Galveston, TX 77555 USA

[9] UT MD Anderson Canc Ctr, Houston, TX USA

来源：

EXPERT REVIEW OF OPHTHALMOLOGY | 2013年 / 8卷 / 06期

关键词：

corticosteroids; non-arteritic anterior ischemic optic neuropathy;

D O I：

10.1586/17469899.2013.852956

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Non-arteritic anterior ischemic optic neuropathy (NAION) is the most common cause of an acute unilateral optic neuropathy in patients older than 50 years of age. Its consequences range from temporarily disabling to permanently blinding. Unfortunately, the pathophysiology of NAION is incompletely understood and no proven effective treatment for NAION currently exists. Numerous theories have been proposed regarding the pathophysiology of NAION including hypoperfusion of the optic nerve, nocturnal hypotension, and in rare cases thrombotic or embolic etiologies. Notably, newer evidence has implicated possible inflammatory processes in NAION leading to potential, theoretical benefit from corticosteroid treatment. This review will spotlight the pros and cons of corticosteroid treatment in NAION.

引用

页码：577 / 580

页数：4

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