FLOW-INJECTION EXTRACTION-SPECTROPHOTOMETRIC DETERMINATION OF IMIPRAMINE IN PHARMACEUTICALS WITH METHYL-ORANGE

被引：21

作者：

PEREZRUIZ, T

MARTINEZLOZANO, C

SANZ, A

ALONSO, C

机构：

[1] Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia

来源：

TALANTA | 1994年 / 41卷 / 09期

关键词：

D O I：

10.1016/0039-9140(94)E0062-V

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Imipramine in aqueous solution is extracted into 1,2-dichloroethane as its ion-pair with Methyl Orange in an unsegmented flow system and quantified spectrophotometrically. A linear calibration graph was obtained between 0.79 and 25.3 mug/ml of imipramine. Up to 45 samples/hr can be processed with a RSD of 0.88-1.6%. The method was satisfactorily applied to the determination of imipramine in pharmaceutical preparations.

引用

页码：1523 / 1527

页数：5

共 31 条

[1]

ALARY J, 1976, ANN PHARM FR, V34, P419

[2]

BELTAGY YA, 1976, PHARMAZIE, V31, P483

[3] ELECTROANALYTICAL STUDY OF TRICYCLIC ANTIDEPRESSANTS [J].