CYTOTOXICITY ON L1210 LEUKEMIC-CELLS OF BETA-AMANITIN CONCANAVALIN-A AND PHALLACIDIN CONCANAVALIN-A CONJUGATES

被引：5

作者：

ZHELEV, Z

ILARIONOVA, M

ZHELEVA, A

ALEXIEV, C

HALACHEVA, K

TODOROV, D

机构：

[1] ACAD MED SOFIA,NAT ONCOL CTR,SOFIA,BULGARIA

[2] UNIV PLEVEN,SCH MED,GASTROENTEROL CLIN,PLEVEN,BULGARIA

来源：

TOXICON | 1990年 / 28卷 / 11期

关键词：

D O I：

10.1016/0041-0101(90)90102-D

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Z. Zhelev, M. Ilarionova, A. Zheleva, C. Alexiev, K. Halacheva and D. Todorov. Cytoxicity on L1210 leukemic cells of beta-amanitin-concanavalin A and phallacidin-concanavalin A conjugates. Toxicon 28, 1360-1363, 1990.-The conjugates beta-amanitin-concanavalin A and phallacidin concanavalin A were tested for direct cytotoxicity on L1210 lymphocytic leukemia cells by a combined in vitro-in vivo bioassay. Both conjugates exerted strong direct cytotoxicity on the tumour cells. © 1990.

引用

页码：1360 / 1363

页数：4

共 11 条

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[2]

FAULSTICH H, 1985, METHOD ENZYMOL, V112, P225, DOI 10.1016/S0076-6879(85)12019-7

[3] SELECTIVE TOXICITY OF AMANITIN-ALBUMIN CONJUGATES FOR MACROPHAGES [J].