Dyarrheal Syndrome in a Patient Co-Infected with Leishmania infantum and Schistosoma mansoni

被引：8

作者：

Cota, Glaucia Fernandes ^{[1
,2
]}

Gomes, Luciana Inacia ^{[2
]}

Pinto, Bruna Fernandes ^{[2
]}

Santos-Oliveira, Joanna R. ^{[3
]}

Da-Cruz, Alda Maria ^{[3
]}

Pedrosa, Moises Salgado ^{[1
]}

Tafuri, Wagner Luiz ^{[4
]}

Rabello, Ana ^{[2
]}

机构：

[1] Fundacao Hosp Estado Minas Gerais Fhemig, Hosp Eduardo Menezes, Rua Dr Cristiano Resende 2213, BR-30622020 Belo Horizonte, MG, Brazil

[2] Inst Oswaldo Cruz FIOCRUZ, Ctr Pesquisas Rene Rachou, Lab Pesquisas Clin, BR-30190002 Belo Horizonte, MG, Brazil

[3] Inst Oswaldo Cruz FIOCRUZ, Lab Interdisciplinar Pesquisas Med, BR-21040360 Rio De Janeiro, RJ, Brazil

[4] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Patol Geral, BR-31270901 Belo Horizonte, MG, Brazil

来源：

CASE REPORTS IN MEDICINE | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/240512

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This case report describes an atypical clinical presentation of visceral leishmaniasis affecting the digestive tract and causing malabsorption syndrome in a patient without recognized immunosuppressive condition. After appropriate treatment for the classical visceral form of the disease, diarrhea persisted as the main symptom and massive infection by Leishmania was detected by histopathology analysis of the duodenal mucosa. Schistosoma mansoni coinfection was also confirmed and treated without impact on diarrhea. New course of amphotericin B finally led to complete improvement of diarrhea. Atypical visceral leishmaniasis involving the gastrointestinal tract is well recognized in HIV coinfection but very rare in immunocompetent patients. The factors determining the control or evolution of the Leishmania infection have not been completely identified. This case stresses the importance of atypical symptoms and the unusual location of visceral leishmaniasis, not only in immunodepressed patients, and raises the possible influence of chronic infection by S. mansoni reducing the immune response to Leishmania.

引用

页数：4

共 27 条

[1] Unusual duodenal presentation of leishmaniasis [J].