A PRACTICAL STEREOSELECTIVE SYNTHESIS OF (2S,4S)4-TERT-BUTOXYCARBONYLAMINO-2-METHYLPYRROLIDINE

被引：11
|
作者：
LI, Q
CHU, DTW
RAYE, K
CLAIBORNE, A
SEIF, L
MACRI, B
PLATTNER, JJ
机构：
[1] Abbott Laboratories, Abbott Park, IL 60064-3500
来源：
TETRAHEDRON LETTERS | 1995年 / 36卷 / 46期
关键词：
D O I：
10.1016/0040-4039(95)01813-W
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.
引用
收藏
页码：8391 / 8394
页数：4
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