INVITRO ACTIVITY OF CP-99,219, A NEW FLUOROQUINOLONE, AGAINST CLINICAL ISOLATES OF GRAM-POSITIVE BACTERIA

被引：126
作者：
ELIOPOULOS, GM
KLIMM, K
ELIOPOULOS, CT
FERRARO, MJ
MOELLERING, RC
机构：
[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[2] MASSACHUSETTS GEN HOSP,DEPT MED,BOSTON,MA 02114
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 02期
关键词：
D O I：
10.1128/AAC.37.2.366
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The in vitro activity of the fluoroquinolone CP-99,219 against gram-positive bacteria was compared with those of five other antimicrobial agents. Against ciprofloxacin-susceptible staphylococci and against streptococci, MICs were less-than-or-equal-to 0.12 and less-than-or-equal-to 0.5 mug/ml, respectively. CP-99,219 was also more active than ciprofloxacin against ciprofloxacin-resistant staphylococci, most enterococci, Leuconostoc spp., and lactobacilli.
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页码：366 / 370
页数：5
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