DEVELOPMENT OF CHIRAL STABILIZED AZOMETHINE YLIDS - COMPLETING THE MEMORY RELAY

被引：41
作者：
ANSLOW, AS
HARWOOD, LM
PHILLIPS, H
WATKIN, D
机构：
[1] UNIV OXFORD,DYSON PERRINS LAB,S PK RD,OXFORD OX1 3QY,ENGLAND
[2] UNIV OXFORD,CHEM CRYSTALLOG LAB,OXFORD OX1 3PD,ENGLAND
来源：
TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 10期
关键词：
D O I：
10.1016/S0957-4166(00)86146-7
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
We report how the alpha-chirality of L-valine can be "memorised" through a sequence involving chirality transfer to a cyclic template, followed by azomethine ylid generation and enantiospecific cycloaddition to regenerate the centre lost during ylid formation. Subsequent removal of the chiral template furnishes alpha-substituted D-proline derivatives.
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页码：997 / 1000
页数：4
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