Antiulcer and hepatoprotective effects of Semicarpus anacardium Linn. seed extract

被引：0

作者：

Ahmed, Md. Liyakat ^{[1
]}

Jadhav, Ashwini ^{[1
]}

Swamy, Paramjyothi ^{[2
]}

Sanaullah, Syed ^{[1
]}

Kumar, N. Santosh ^{[1
]}

机构：

[1] Luqman Coll Pharm, Dept Pharmacol, Gulbarga 585106, Karnataka, India

[2] Gulbarga Univ, Dept Biochem, Gulbarga 585106, Karnataka, India

来源：

ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL | 2012年 / 1卷 / 01期

关键词：

Semicarpus anacardium; Antiulcer; Hepatoprotective; Asprin; pylorus ligation;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The antiulcer effect of Semicarpus anacardium Linn. seed extracts was investigated against aspirin plus pylorus ligation induced and ethanol induced gastric ulcers in rats. Both the models revealed ulcer healing property of the seed extracts. The present investigation also revealed the hepatoprotective activity of the seed extracts, against ethanol induced hepatotoxicity. Histopathological studies of the liver showed significant restoration of the normal histomorphological pattern of hepatocytes. The biochemical estimation of serum bilirubin, serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT) and alkaline phosphatase (ALP) showed significant reduction in the rats fed with the seed extracts. The study, thus, substantiates the potential anticulcer and hepatoprotective effects of Semicarpus anacardium seeds.

引用

页码：105 / 109

页数：5

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