EFFICIENT SYNTHESIS OF 2'-AMINO-2'-DEOXYPYRIMIDINE 5'-TRIPHOSPHATES

被引：25

作者：

MCGEE, DPC ^{[1
]}

VARGEESE, C ^{[1
]}

ZHAI, YS ^{[1
]}

KIRSCHENHEUTER, GP ^{[1
]}

SETTLE, A ^{[1
]}

SIEDEM, CR ^{[1
]}

PIEKEN, WA ^{[1
]}

机构：

[1] NEXAGEN INC,BOULDER,CO 80301

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 06期

关键词：

D O I：

10.1080/15257779508010694

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of 2'-amino-2'-deoxypyrimidine 5'-triphosphates is described. The 2'-amino-2'-deoxyuridine 5'-triphosphate is obtained from uridine in four steps with 25% overall yield. The 2'-amino-2'-deoxycytidine 5'-triphosphate is obtained from uridine in seven steps with 13% overall yield.

引用

页码：1329 / 1339

页数：11

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