A NEW-AGE FOR MAMMALIAN PLASMA-MEMBRANE AMINO-ACID TRANSPORTERS

被引：35
作者：
BERTRAN, J
TESTAR, X
ZORZANO, A
PALACIN, M
机构：
[1] UNIV BARCELONA,FAC BIOL,DEPT BIOQUIM & FISIOL,E-08028 BARCELONA,SPAIN
[2] INST RECERCA ONCOL,DEPT CRIOBIOL & TERAPIA CELULAR,BARCELONA,SPAIN
来源：
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY | 1994年 / 4卷 / 5-6期
关键词：
AMINO ACID TRANSPORT; TRANSPORTER STRUCTURE; TRANSPORTER EXPRESSION; PLASMA MEMBRANE;
D O I：
10.1159/000154728
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A wealth of structural information on amino acid transport-related proteins has appeared during the last 4 years. Up to date, these proteins are structurally classified into five different families: cationic amino acid transporters; superfamily of sodium- and chloride-dependent transporters; family of glutamate transporters, which includes structurally related zwitterionic amino acid transporters; family of sodium symporters for sugars, amino acids, vitamins and nucleosides; and a family of possible specific activators or subunits of amino acid transporters. The present review deals with the structural classification of different amino acid transport-related proteins as well as with their functional characterization.
引用
收藏
页码：217 / 241
页数：25
相关论文
共 87 条
[11]   ROLE OF AMINO-ACID-TRANSPORT AND COUNTERTRANSPORT IN NUTRITION AND METABOLISM [J].
CHRISTENSEN, HN .
PHYSIOLOGICAL REVIEWS, 1990, 70 (01) :43-77
[12]  
CHRISTENSEN HN, 1993, NUTR REV, V51, P95, DOI 10.1111/j.1753-4887.1993.tb03080.x
[13]  
CLOSS EI, 1993, J BIOL CHEM, V268, P7538
[14]  
DEGUCHI Y, 1990, J BIOL CHEM, V265, P21704
[15]   IDENTIFICATION OF A NEW TRANSPORT-SYSTEM (Y+L) IN HUMAN ERYTHROCYTES THAT RECOGNIZES LYSINE AND LEUCINE WITH HIGH-AFFINITY [J].
DEVES, R ;
CHAVEZ, P ;
BOYD, CAR .
JOURNAL OF PHYSIOLOGY-LONDON, 1992, 454 :491-501
[16]   MOLECULAR-CLONING AND EXPRESSION OF A HIGH-AFFINITY L-PROLINE TRANSPORTER EXPRESSED IN PUTATIVE GLUTAMATERGIC PATHWAYS OF RAT-BRAIN [J].
FREMEAU, RT ;
CARON, MG ;
BLAKELY, RD .
NEURON, 1992, 8 (05) :915-926
[17]   D-PENICILLAMINE AND THE TRANSPORT OF L-CYSTINE BY RAT AND HUMAN RENAL CORTICAL BRUSH-BORDER MEMBRANE-VESICLES [J].
FURLONG, TJ ;
POSEN, S .
AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 258 (02) :F321-F327
[18]  
FURRIOLS M, 1993, J BIOL CHEM, V268, P27060
[19]   THE MOUSE PINK-EYED DILUTION GENE - ASSOCIATION WITH HUMAN PRADER-WILLI AND ANGELMAN SYNDROMES [J].
GARDNER, JM ;
NAKATSU, Y ;
GONDO, Y ;
LEE, S ;
LYON, MF ;
KING, RA ;
BRILLIANT, MH .
SCIENCE, 1992, 257 (5073) :1121-1124
[20]   CLONING, EXPRESSION, AND LOCALIZATION OF A RAT-BRAIN HIGH-AFFINITY GLYCINE TRANSPORTER [J].
GUASTELLA, J ;
BRECHA, N ;
WEIGMANN, C ;
LESTER, HA ;
DAVIDSON, N .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (15) :7189-7193
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