A NEW-AGE FOR MAMMALIAN PLASMA-MEMBRANE AMINO-ACID TRANSPORTERS

被引：35
作者：
BERTRAN, J
TESTAR, X
ZORZANO, A
PALACIN, M
机构：
[1] UNIV BARCELONA,FAC BIOL,DEPT BIOQUIM & FISIOL,E-08028 BARCELONA,SPAIN
[2] INST RECERCA ONCOL,DEPT CRIOBIOL & TERAPIA CELULAR,BARCELONA,SPAIN
来源：
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY | 1994年 / 4卷 / 5-6期
关键词：
AMINO ACID TRANSPORT; TRANSPORTER STRUCTURE; TRANSPORTER EXPRESSION; PLASMA MEMBRANE;
D O I：
10.1159/000154728
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A wealth of structural information on amino acid transport-related proteins has appeared during the last 4 years. Up to date, these proteins are structurally classified into five different families: cationic amino acid transporters; superfamily of sodium- and chloride-dependent transporters; family of glutamate transporters, which includes structurally related zwitterionic amino acid transporters; family of sodium symporters for sugars, amino acids, vitamins and nucleosides; and a family of possible specific activators or subunits of amino acid transporters. The present review deals with the structural classification of different amino acid transport-related proteins as well as with their functional characterization.
引用
收藏
页码：217 / 241
页数：25
相关论文
共 87 条
[1]   THE HUMAN CATIONIC AMINO-ACID TRANSPORTER (ATRC1) - PHYSICAL AND GENETIC-MAPPING TO 13Q12-Q14 [J].
ALBRITTON, LM ;
BOWCOCK, AM ;
EDDY, RL ;
MORTON, CC ;
TSENG, L ;
FARRER, LA ;
CAVALLISFORZA, LL ;
SHOWS, TB ;
CUNNINGHAM, JM .
GENOMICS, 1992, 12 (03) :430-434
[2]   A PUTATIVE MURINE ECOTROPIC RETROVIRUS RECEPTOR GENE ENCODES A MULTIPLE MEMBRANE-SPANNING PROTEIN AND CONFERS SUSCEPTIBILITY TO VIRUS-INFECTION [J].
ALBRITTON, LM ;
TSENG, L ;
SCADDEN, D ;
CUNNINGHAM, JM .
CELL, 1989, 57 (04) :659-666
[3]   NEUROTRANSMITTER TRANSPORTERS - A TALE OF 2 FAMILIES [J].
AMARA, SG .
NATURE, 1992, 360 (6403) :420-421
[4]   NEUROTRANSMITTER TRANSPORTERS - RECENT PROGRESS [J].
AMARA, SG ;
KUHAR, MJ .
ANNUAL REVIEW OF NEUROSCIENCE, 1993, 16 :73-93
[5]  
ARRIZA JL, 1993, J BIOL CHEM, V268, P15329
[6]   IDENTIFICATION OF DOMAINS OF A CLONED RAT-BRAIN GABA TRANSPORTER WHICH ARE NOT REQUIRED FOR ITS FUNCTIONAL EXPRESSION [J].
BENDAHAN, A ;
KANNER, BI .
FEBS LETTERS, 1993, 318 (01) :41-44
[7]  
BERTELOOT A, 1990, COMP PHYSL, V7, P130
[8]  
BERTRAN J, 1993, J BIOL CHEM, V268, P14842
[9]   EXPRESSION CLONING OF A CDNA FROM RABBIT KIDNEY CORTEX THAT INDUCES A SINGLE TRANSPORT-SYSTEM FOR CYSTINE AND DIBASIC AND NEUTRAL AMINO-ACIDS [J].
BERTRAN, J ;
WERNER, A ;
MOORE, ML ;
STANGE, G ;
MARKOVICH, D ;
BIBER, J ;
TESTAR, X ;
ZORZANO, A ;
PALACIN, M ;
MURER, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5601-5605
[10]   STIMULATION OF SYSTEM Y+-LIKE AMINO-ACID-TRANSPORT BY THE HEAVY-CHAIN OF HUMAN 4F2 SURFACE-ANTIGEN IN XENOPUS-LAEVIS OOCYTES [J].
BERTRAN, J ;
MAGAGNIN, S ;
WERNER, A ;
MARKOVICH, D ;
BIBER, J ;
TESTAR, X ;
ZORZANO, A ;
KUHN, LC ;
PALACIN, M ;
MURER, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5606-5610
123456789