ASSOCIATION OF DIETARY AND LIFE-STYLE FACTORS WITH SEX-HORMONES IN POSTMENOPAUSAL WOMEN

被引：85
作者：
NEWCOMB, PA
KLEIN, R
KLEIN, BEK
HAFFNER, S
MARESPERLMAN, J
CRUICKSHANKS, KJ
MARCUS, PM
机构：
[1] University of Wisconsin Comprehensive Cancer Center, University of Wisconsin, Madison, WI
[2] Department of Ophthalmology, University of Wisconsin Medical School, Madison, WI
[3] Division of Endocrinology and Metabolism, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX
来源：
EPIDEMIOLOGY | 1995年 / 6卷 / 03期
关键词：
DIET; DIHYDROEPIANDROSTERONE SULFATE; ESTRONE; SEX-HORMONE-BINDING GLOBULIN; TESTOSTERONE; ALCOHOL; MENOPAUSE; ASPIRIN;
D O I：
10.1097/00001648-199505000-00022
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
We examined the relations between endogenous sex hormones and alcohol intake, dietary constituents, and life-style factors in a population based sample of 253 postmenopausal women not using replacement hormones. Estrone, dihydroepiandrosterone sulfate (DHEA-S), sex hormone-binding globulin (SHBG), and free and total testosterone were measured in serum. Age and years since menopause were negatively associated with dihydroepiandrosterone sulfate and positively associated with sex hormone-binding globulin levels. Higher relative weight was strongly and negatively associated with sex hormone-binding globulin. Other factors were only very weakly associated with sex hormones. Since, except for weight, few potentially modifiable factors appear to influence these hormone profiles, it may be that behaviors earlier in life mediate hormone levels and subsequent disease risk.
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收藏
页码：318 / 321
页数：4
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