MINOR BIOACTIVE POLYACETYLENES FROM PETROSIA-FICIFORMIS

被引：42

作者：

CIMINO, G ^{[1
]}

DEGIULIO, A ^{[1
]}

DEROSA, S ^{[1
]}

DIMARZO, V ^{[1
]}

机构：

[1] CNR,INST CHIM MOLEC INTERESSE BIOL,VIA TOIANO 6,ARCO FELICE,ITALY

来源：

JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 02期

关键词：

D O I：

10.1021/np50068a012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six novel minor polyacetylenic metabolites were isolated from the marine sponge Petrosia ficiformis by means of bioassay-directed purification. Spectral analysis led to partial structure determination, and the brine shrimp lethality assay on the pure compounds allowed a structure/activity relationship study. The potato disc antitumor assay and tests for the inhibition of fertilized sea urchin eggs were also conducted on the most abundant compounds. © 1990, American Chemical Society. All rights reserved.

引用

页码：345 / 353

页数：9

共 12 条

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