A facile microwave assisted one-pot synthesis of novel 1-methylhexahydroquinazolin-5(6H)-ones and bis-1-methylhexahydroquinazolin-5(6H)ones

被引：0

作者：

Saha, Madhusudhan ^{[1
]}

Karim, Enamul ^{[1
]}

Helissey, Philippe ^{[2
]}

Vishwakarma, Jai N. ^{[1
]}

Nongkhlaw, Rishanlang ^{[3
]}

机构：

[1] St Anthonys Coll, Dept Chem, Organ Res Lab, Shillong 793001, Meghalaya, India

[2] Univ Paris 05, Fac Sci Pharmaceut & Biolog, CNRS, Chim Therapeut Lab,UMR 8638, F-75270 Paris 06, France

[3] North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India

来源：

ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY | 2010年 / 2卷 / 03期

关键词：

hexahydroquinazolin-5(6H)-ones; bis-hexahydroquinazolin-5(6H)-ones; dimedone; enaminone; 1,3-cyclohexanedione;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel hexahydroquinazolin-5(6H)-ones 3a-j have been synthesized in good yields by the reaction of enaminones 2a-b with primary amines and formaldehyde under the influence microwaves. Enaminones 2a-b have also been reacted with diamines and formaldehyde under similar conditions resulting in hitherto unreported bishexahydroquinazolin-5(6H)-ones 4a-d and 5a-d. The structures of the molecules have been established with the help of spectral and analytical data.

引用

页码：263 / 270

页数：8