A facile microwave assisted one-pot synthesis of novel 1-methylhexahydroquinazolin-5(6H)-ones and bis-1-methylhexahydroquinazolin-5(6H)ones

被引：0

作者：

Saha, Madhusudhan ^{[1
]}

Karim, Enamul ^{[1
]}

Helissey, Philippe ^{[2
]}

Vishwakarma, Jai N. ^{[1
]}

Nongkhlaw, Rishanlang ^{[3
]}

机构：

[1] St Anthonys Coll, Dept Chem, Organ Res Lab, Shillong 793001, Meghalaya, India

[2] Univ Paris 05, Fac Sci Pharmaceut & Biolog, CNRS, Chim Therapeut Lab,UMR 8638, F-75270 Paris 06, France

[3] North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India

来源：

ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY | 2010年 / 2卷 / 03期

关键词：

hexahydroquinazolin-5(6H)-ones; bis-hexahydroquinazolin-5(6H)-ones; dimedone; enaminone; 1,3-cyclohexanedione;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel hexahydroquinazolin-5(6H)-ones 3a-j have been synthesized in good yields by the reaction of enaminones 2a-b with primary amines and formaldehyde under the influence microwaves. Enaminones 2a-b have also been reacted with diamines and formaldehyde under similar conditions resulting in hitherto unreported bishexahydroquinazolin-5(6H)-ones 4a-d and 5a-d. The structures of the molecules have been established with the help of spectral and analytical data.

引用

页码：263 / 270

页数：8

共 34 条

[31] Facile eco-friendly synthesis of 3,4,6,7-tetrahydro-3,3,6,6-tetramethyl-2H-xanthene 1,8(5H,9H)-dione, crystal structure and theoretical study
N. Tarannum
M. Singh
Crystallography Reports, 2014, 59 : 987 - 992
[32] An expeditious and green one-pot synthesis of 12-substituted-3,3-dimethyl-3,4,5,12-tetrahydrobenzo[b]acridine-1,6,11(2H)-triones
Saiedeh Kamalifar
Hamzeh Kiyani
Research on Chemical Intermediates, 2019, 45 : 5975 - 5987
[33] An expeditious and green one-pot synthesis of 12-substituted-3,3-dimethyl-3,4,5,12-tetrahydrobenzo[b]acridine-1,6,11(2H)-triones
Kamalifar, Saiedeh
Kiyani, Hamzeh
RESEARCH ON CHEMICAL INTERMEDIATES, 2019, 45 (12) : 5975 - 5987
[34] Synthesis and X-ray analysis of butyl and glycosyl (2-arylamino-4,4-dimethyl-6-oxocyclohex-1-ene)carbodithioates and their possible cyclization to 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives
El Ashry, El Sayed H.
Aly, Aly A.
Amer, Mohammed R.
Shah, Muhammad R.
Ng, Seik W.
CARBOHYDRATE RESEARCH, 2011, 346 (02) : 169 - 176

← 1 2 3 4 →