What is new in systemic lupus erythematosus

Systemic lupus erythematosus is a heterogeneous rheumatic systemic disease with extremely varied clinical manifestations and a diverse pathogenesis, as illustrated in this review on the most relevant new knowledge related to the disease. Topics such as anemia, pathogenesis, cardiovascular risk assessment, anti phospholipid syndrome, prediction of damage and recent advances in treatment, including tolerogenic and biological agents, are discussed. Relevant contributions regarding classical therapies such ascorticosteroid and antimalarials and their optimal use, as well as the roll of vitamin D, are also referred. (C) 2014 Elsevier Espana, S.L.U. All rights reserved.