SEPARATION OF CARRIER-FREE SC-47 FROM TITANIUM TARGETS

被引：36
作者：
PIETRELLI, L [1 ]
MAUSNER, LF [1 ]
KOLSKY, KL [1 ]
机构：
[1] BROOKHAVEN NATL LAB,DEPT MED,UPTON,NY 11973
来源：
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES | 1992年 / 157卷 / 02期
关键词：
D O I：
10.1007/BF02047448
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The radiochemical separation of no-carrier-added (NCA) Sc-47 from (nat)Ti targets has been studied. Scandium-47, a medium-energy beta-emitter, is intended for use with labelled tumor associated monoclonal antibodies for radiotherapy. Several radiochemical methods for the separation of NCA Sc-47 from macroquantities of titanium and other impurities were tested. Four different procedures based on ion exchange, solvent extraction and extraction chromatography are reported. For each method, parameters such as the distribution coefficient, kinetics and recoveries are reported. The selective separation can be performed rapidly by all methods.
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页码：335 / 345
页数：11
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