METABOLISM AND TOXICITY OF SYNTHETIC ANALOGS OF MACROCYCLIC DIESTER PYRROLIZIDINE ALKALOIDS

被引：37

作者：

MATTOCKS, AR ^{[1
]}

DRIVER, HE ^{[1
]}

BARBOUR, RH ^{[1
]}

ROBINS, DJ ^{[1
]}

机构：

[1] UNIV GLASGOW,DEPT CHEM,GLASGOW G12 8QQ,SCOTLAND

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1986年 / 58卷 / 01期

关键词：

D O I：

10.1016/S0009-2797(86)80089-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：95 / 108

页数：14

共 17 条

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[2]

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[3] PYRROLIZIDINE ALKALOID ANALOGS - SYNTHESIS OF 10-MEMBERED MACROCYCLIC DIESTERS OF (+)-RETRONECINE [J].

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ROBINS, DJ .

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[4] MALATHION POTENTIATION AND INHIBITION OF HYDROLYSIS OF VARIOUS CARBOXYLIC ESTERS BY TRIORTHOTOLYL PHOSPHATE (TOTP) IN MICE [J].

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[5] PYRROLIZIDINE ALKALOID ANALOGS - SYNTHESIS OF 11-MEMBERED MACROCYCLIC DIESTERS OF RETRONECINE [J].

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[6]

DRIVER HE, 1984, CHEM-BIOL INTERACT, V51, P201

[7]

Mattocks A. R., 1978, Effects of poisonous plants on livestock,, P177

[8] RELATION OF STRUCTURAL FEATURES TO PYRROLIC METABOLITES IN LIVERS OF RATS GIVEN PYRROLIZIDINE ALKALOIDS AND DERIVATIVES [J].

MATTOCKS, AR .

CHEMICO-BIOLOGICAL INTERACTIONS, 1981, 35 (03) :301-310

[9] PYRROLIC AND N-OXIDE METABOLITES FORMED FROM PYRROLIZIDINE ALKALOIDS BY HEPATIC MICROSOMES INVITRO - RELEVANCE TO INVIVO HEPATOTOXICITY [J].

MATTOCKS, AR ;

BIRD, I .

CHEMICO-BIOLOGICAL INTERACTIONS, 1983, 43 (02) :209-222

[10] SYNTHETIC COMPOUNDS WITH TOXIC PROPERTIES SIMILAR TO THOSE OF PYRROLIZIDINE ALKALOIDS AND THEIR PYRROLIC METABOLITES [J].

MATTOCKS, AR .

NATURE, 1971, 232 (5311) :476-&

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