ON INTERACTION OF ACTIVE SITE OF ALPHA-CHYMOTRYPSIN WITH CHROMOPHORES - PROFLAVIN BINDING AND ENZYME CONFORMATION DURING CATALYSIS

被引:172
作者
BERNHARD, SA
LEE, BF
TASHJIAN, ZH
机构
关键词
D O I
10.1016/S0022-2836(66)80033-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
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页码:405 / &
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[1]   SPECTROPHOTOMETRIC INVESTIGATIONS OF MECHANISM OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSES - DETECTION OF ACYL-ENZYME INTERMEDIATE [J].
BENDER, ML ;
ZERNER, B ;
SCHONBAUM, GR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (13) :2540-+
[2]   PH DEPENDENCE OF SOME ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSES [J].
BENDER, ML ;
SCHONBAUM, GR ;
ZERNER, B .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (13) :2562-&
[3]  
BENDER ML, 1962, J AM CHEM SOC, V84, P2582, DOI 10.1021/ja00872a024
[4]   CURRENT STATUS OF ALPHA-CHYMOTRYPSIN MECHANISM [J].
BENDER, ML ;
KEZDY, FJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (18) :3704-&
[5]   KINETIC ISOTOPE EFFECTS OF DEUTERIUM OXIDE ON SEVERAL ALPHA-CHYMOTRYPSIN-CATALYZED REACTIONS [J].
BENDER, ML ;
HAMILTON, GA .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (13) :2570-&
[6]   SPECTROPHOTOMETRIC IDENTIFICATION OF ACYL ENZYME INTERMEDIATES [J].
BERNHARD, SA ;
LAU, SJ ;
NOLLER, H .
BIOCHEMISTRY, 1965, 4 (06) :1108-&
[7]   OPTICAL DETECTION OF TRANSIENTS IN TRYPSIN- AND CHYMOTRYPSIN-CATALYZED REACTIONS [J].
BERNHARD, SA ;
GUTFREUND, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 53 (06) :1238-+
[8]   MECHANISM OF ENZYME INHIBITION BY PHOSPHATE ESTERS [J].
BERNHARD, SA ;
ORGEL, LE .
SCIENCE, 1959, 130 (3376) :625-626
[9]   KINETICS OF THE SYSTEM ALPHA-CHYMOTRYPSIN METHYL HIPPURATE WATER HYDROXYLAMINE - THE ROLE OF WATER IN ENZYMATIC HYDROLYSIS [J].
BERNHARD, SA ;
COLES, WC ;
NOWELL, JF .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1960, 82 (12) :3043-3050