POTENTIAL BIOLOGICAL TARGETS FOR ANTI-ALZHEIMER DRUGS

被引:13
作者
ALLAIN, H
BELLIARD, S
DECERTAINES, J
BENTUEFERRER, D
BUREAU, M
LACROIX, P
机构
[1] HOP PONTCHAILLOU,SERV NEUROL,RENNES,FRANCE
[2] FAC MED RENNES,RESONANCE MAGNET BIOL & MED LAB,RENNES,FRANCE
[3] BIOTRIAL SA,RENNES,FRANCE
来源
DEMENTIA | 1993年 / 4卷 / 06期
关键词
ALZHEIMERS DISEASE; PHYSIOPATHOLOGY; CLINICAL TRIALS;
D O I
10.1159/000107344
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The stunning accumulation of data on the physiopathology of Alzheimer's disease is a real hinderance to pharmacologists who have to make decisions as to what molecules should be assessed first in man. Considering the cumbersomeness and cost of clinical trials in that field, a review of potential targets for drugs that are supposed to be active against the disease has become necessary, for a true definition of the rational justifications of trials to be envisaged.
引用
收藏
页码:347 / 352
页数:6
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