NEUROENDOCRINE CELLS - A NEW PROGNOSTIC PARAMETER IN PROSTATE-CANCER

被引：147
作者：
COHEN, RJ [1 ]
GLEZERSON, G [1 ]
HAFFEJEE, Z [1 ]
机构：
[1] UNIV WITWATERSRAND,S AFRICAN INST MED RES,DEPT UROL,JOHANNESBURG 2193,SOUTH AFRICA
来源：
BRITISH JOURNAL OF UROLOGY | 1991年 / 68卷 / 03期
关键词：
D O I：
10.1111/j.1464-410X.1991.tb15318.x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.
引用
收藏
页码：258 / 262
页数：5
相关论文
共 10 条
[1]   PEPTIDE-HORMONE AND SEROTONIN-IMMUNOREACTIVE CELLS IN NORMAL AND HYPERPLASTIC PROSTATE-GLANDS [J].
ABRAHAMSSON, PA ;
WADSTROM, LB ;
ALUMETS, J ;
FALKMER, S ;
GRIMELIUS, L .
PATHOLOGY RESEARCH AND PRACTICE, 1986, 181 (06) :675-683
[2]   ARGENTAFFIN CELLS IN PROSTATIC CARCINOMA - DIFFERENTIATION FROM LIPOFUSCIN AND MELANIN IN PROSTATIC EPITHELIUM [J].
AZZOPARDI, JG ;
EVANS, DJ .
JOURNAL OF PATHOLOGY, 1971, 104 (04) :247-+
[3]   PROSTATIC-CARCINOMA - HISTOLOGICAL AND IMMUNOHISTOLOGICAL FACTORS AFFECTING PROGNOSIS [J].
COHEN, RJ ;
GLEZERSON, G ;
HAFFEJEE, Z ;
AFRIKA, D .
BRITISH JOURNAL OF UROLOGY, 1990, 66 (04) :405-410
[4]  
DISANTAGNESE PA, 1987, HUM PATHOL, V18, P849
[5]  
Gleason DF, 1977, UROLOGIC PATHOLOGY P, P171
[6]  
HARADA M, 1977, CANCER TREAT REP, V61, P223
[7]  
Jewett H J, 1975, Urol Clin North Am, V2, P105
[8]   IMMUNOHISTOCHEMICAL DETECTION OF CHROMOGRANIN AND NEURON-SPECIFIC ENOLASE IN PANCREATIC ENDOCRINE NEOPLASMS [J].
LLOYD, RV ;
MERVAK, T ;
SCHMIDT, K ;
WARNER, TFCS ;
WILSON, BS .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1984, 8 (08) :607-614
[9]  
TURBATHERRERA EA, 1988, ARCH PATHOL LAB MED, V112, P1100
[10]  
WILSON F, 1985, WILLIAMS TXB ENDOCRI, P515
1