PRESENCE AND SPECIFIC CONCENTRATION OF CARBONIC ANHYDRASE-II IN MATRIX VESICLES

被引：16
作者：
STECHSCHULTE, DJ
MORRIS, DC
SILVERTON, SF
ANDERSON, HC
VAANANEN, HK
机构：
[1] UNIV OULU,DEPT ANAT,SF-90100 OULU 10,FINLAND
[2] UNIV PENN,SCH DENT MED,DEPT ORAL MED,PHILADELPHIA,PA 19104
来源：
BONE AND MINERAL | 1992年 / 17卷 / 02期
关键词：
D O I：
10.1016/0169-6009(92)90734-U
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Matrix vesicles were isolated from the epiphyseal growth plates of normal weanling rats. and the presence of carbonic anhydrase II was demonstrated by Western blotting and ultrastructural immunolocalization using the immunogold technique. Total carbonic anhydrase activity was assayed and showed a statistically significant increase in matrix vesicles as compared to normal rat chondrocytes derived from the same growth plates. These results are the first to establish the presence of carbonic anhydrase in matrix vesicles.
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页码：187 / 191
页数：5
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