DIFFERENCES IN VITAMIN-D STATUS BETWEEN COUNTRIES IN YOUNG-ADULTS AND THE ELDERLY

被引:487
作者
MCKENNA, MJ [1 ]
机构
[1] ST VINCENTS HOSP,DEPT ENDOCRINOL & DIABET,DUBLIN 4,IRELAND
关键词
D O I
10.1016/0002-9343(92)90682-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PURPOSE: To compare vitamin D status between countries in young adults and in the elderly. MATERIALS AND METHODS: Reports on vitamin D status (as assessed by serum 25-hydroxyvitamin D) from 1971 to 1990 were reviewed. Studies were grouped according to geographic regions: North America (including Canada and the United States); Scandinavia (including Denmark, Finland, Norway, and Sweden); and Central and Western Europe (including Belgium, France, Germany, Ireland The Netherlands, Switzerland, and the United Kingdom). RESULTS: Vitamin D status varies with the season in young adults and in the elderly, and is lower during the winter in Europe than in both North America and Scandinavia. Oral vitamin D intake is lower in Europe than in both North America and Scandinavia. Hypovitaminosis D and related abnormalities in bone chemistry are most common in elderly residents in Europe but are reported in all elderly populations. CONCLUSIONS: The vitamin D status in young adults and the elderly varies widely with the country of residence. Adequate exposure to summer sunlight is the essential means to ample supply, but oral intake augmented by both fortification and supplementation is necessary to maintain baseline stores. All countries should adopt a fortification policy. It seems likely that the elderly would benefit additionally from a daily supplement of 10-mu-g of vitamin D.
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页码:69 / 77
页数:9
相关论文
共 154 条
[11]   COMPETITIVE BINDING ASSAY FOR VITAMIN-D AND 25-OH VITAMIN-D [J].
BELSEY, R ;
DELUCA, HF ;
POTTS, JT .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1971, 33 (03) :554-+
[12]   RAPID ASSAY FOR 25-HYDROXY-VITAMIN-D3 WITHOUT PREPARATIVE CHROMATOGRAPHY [J].
BELSEY, RE ;
DELUCA, HF ;
POTTS, JT .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1974, 38 (06) :1046-1051
[13]  
Blahos J, 1986, Acta Univ Carol Med (Praha), V32, P333
[14]  
BOUILLON R, 1976, CLIN CHEM, V22, P364
[15]   VITAMIN-D STATUS IN THE ELDERLY - SEASONAL SUBSTRATE DEFICIENCY CAUSES 1,25-DIHYDROXYCHOLECALCIFEROL DEFICIENCY [J].
BOUILLON, RA ;
AUWERX, JH ;
LISSENS, WD ;
PELEMANS, WK .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1987, 45 (04) :755-763
[16]  
BROWN I R F, 1976, Age and Ageing, V5, P127, DOI 10.1093/ageing/5.3.127
[17]   SINGLE DOSE VITAMIN-D TREATMENT FOR OSTEOMALACIA IN THE ELDERLY [J].
BURNS, J ;
PATERSON, CR .
BRITISH MEDICAL JOURNAL, 1985, 290 (6464) :281-282
[18]  
CAMPBELL GA, 1984, LANCET, V2, P386
[19]  
Chalmers J, 1967, J Bone Joint Surg Br, V49, P403
[20]   CALCIUM AND VITAMIN-D SUPPLEMENTS - EFFECTS ON CALCIUM-METABOLISM IN ELDERLY PEOPLE [J].
CHAPUY, MC ;
CHAPUY, P ;
MEUNIER, PJ .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1987, 46 (02) :324-328