A pathogenic non coding RNA that replicates and accumulates in chloroplasts traffics to this organelle through a nuclear-dependent step

被引:9
作者
Gomez, Gustavo [1 ]
Pallas, Vicente [1 ]
机构
[1] Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, CPI, Valencia, Spain
关键词
viroid-plant interaction; Avsunviroidae compartmentalization; intracellular sorting of non coding RNAs; nucleus-chloroplast signaling; non coding RNAs and plant physiology;
D O I
10.4161/psb.20463
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Viroids belonging to the family Avsunviroidae are the only functional RNAs known to traffic selectively into chloroplasts. Subcellular targeting is a critical step in guaranteeing their access to the machineries involved in their replication. However, the host mechanisms exploited by these non coding pathogenic RNAs to be selectively imported into chloroplasts are poorly understood. Recently, we provide evidence supporting the idea that the Avsunviroidae have evolved to subvert a signaling mechanism between the nucleus and chloroplasts to regulate their differential compartmentalization into the chloroplast of infected cells. Here, we discuss our model and previous observations that provide biological relevance to our hypothesis.
引用
收藏
页码:882 / 884
页数:3
相关论文
共 13 条
[1]  
Bussiere F, 1999, J VIROL, V73, P6353
[2]   Long noncoding RNAs in cell biology [J].
Clark, Michael B. ;
Mattick, John S. .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2011, 22 (04) :366-376
[3]   The Biology of Viroid-Host Interactions [J].
Ding, Biao .
ANNUAL REVIEW OF PHYTOPATHOLOGY, 2009, 47 :105-131
[4]   Eggplant latent viroid, the candidate type species for a new genus within the family Avsunviroidae (hammerhead viroids) [J].
Fadda, Z ;
Daròs, JA ;
Fagoaga, C ;
Flores, R ;
Duran-Vila, N .
JOURNAL OF VIROLOGY, 2003, 77 (11) :6528-6532
[5]   Viroids and viroid-host interactions [J].
Flores, R ;
Hernández, C ;
Martínez de Alba, AE ;
Daròs, JA ;
Di Serio, F .
ANNUAL REVIEW OF PHYTOPATHOLOGY, 2005, 43 :117-+
[6]   Studies on Subcellular Compartmentalization of Plant Pathogenic Noncoding RNAs Give New Insights into the Intracellular RNA-Traffic Mechanisms [J].
Gomez, Gustavo ;
Pallas, Vicente .
PLANT PHYSIOLOGY, 2012, 159 (02) :558-+
[7]  
Gomez G, 2010, PLANT SIGNAL BEHAV, V5, P1517, DOI [10.4161/psb.5.11.13711, 10.1371/journal.pone.0012269]
[8]   Noncoding RNA Mediated Traffic of Foreign mRNA into Chloroplasts Reveals a Novel Signaling Mechanism in Plants [J].
Gomez, Gustavo ;
Pallas, Vicente .
PLOS ONE, 2010, 5 (08)
[9]   SUBCELLULAR LOCATION OF AVOCADO SUNBLOTCH VIROID IN AVOCADO LEAVES [J].
MARCOS, JF ;
FLORES, R .
PLANT SCIENCE, 1990, 67 (02) :237-244
[10]   Mutational analysis of eggplant latent viroid RNA processing in Chlamydomonas reinhardtii chloroplast [J].
Martinez, Fernando ;
Marques, Jorge ;
Salvador, Maria L. ;
Daros, Jose-Antonio .
JOURNAL OF GENERAL VIROLOGY, 2009, 90 :3057-3065