AGING AND THE COMPLEXITY OF CARDIOVASCULAR DYNAMICS

被引：366
作者：
KAPLAN, DT
FURMAN, MI
PINCUS, SM
RYAN, SM
LIPSITZ, LA
GOLDBERGER, AL
机构：
[1] BRIGHAM & WOMENS HOSP,BOSTON,MA 02115
[2] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[3] BETH ISRAEL HOSP,BOSTON,MA 02215
[4] COLIN RES AMER,CAMBRIDGE,MA 02139
[5] HEBREW REHABIL CTR AGED,BOSTON,MA 02131
[6] HARVARD UNIV,SCH MED,BOSTON,MA 02115
来源：
BIOPHYSICAL JOURNAL | 1991年 / 59卷 / 04期
关键词：
D O I：
10.1016/S0006-3495(91)82309-8
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Biomedical signals often vary in a complex and irregular manner. Analysis of variability in such signals generally does not address directly their complexity, and so may miss potentially useful information. We analyze the complexity of heart rate and beat-to-beat blood pressure using two methods motivated by nonlinear dynamics (chaos theory). A comparison of a group of healthy elderly subjects with healthy young adults indicates that the complexity of cardiovascular dynamics is reduced with aging. This suggests that complexity of variability may be a useful physiological marker.
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页码：945 / 949
页数：5
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