MODELING THE REACTIVITY OF ALPHA-KETOGLUTARATE-DEPENDENT NONHEME IRON(II)-CONTAINING ENZYMES

被引：59

作者：

HA, EH ^{[1
]}

HO, RYN ^{[1
]}

KISIEL, JF ^{[1
]}

VALENTINE, JS ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,DEPT CHEM & BIOCHEM,LOS ANGELES,CA 90095

来源：

INORGANIC CHEMISTRY | 1995年 / 34卷 / 09期

关键词：

D O I：

10.1021/ic00113a002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An Fe(II) complex of tris(pyrazolyl)borate and benzoylformate was prepared and reacted with dioxygen in the presence of olefins. In the caes of cyclohexene, cyclohexene oxide was produced in 35-40% yield. In the case of cis- and trans-stilbene, the former was found to react to give cis-stilbene oxide in 50-60% yield and a small amount of benzaldehyde; no trans-oxide was observed. The latter gave no reaction. This system is proposed as a possible model for reactions of alpha-ketoglutarate-dependent Fe(II)-containing dioxygenase enzymes. [GRAPHICS]

引用

页码：2265 / 2266

页数：2

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