SYNTHESIS AND ANTICONVULSANT PROPERTIES OF SOME NOVEL QUINAZOLONE-THIOSEMICARBAZONE AND 4-THIAZOLIDONE DERIVATIVES

Diverse biological activities have been found in compounds having a quinazolinone ring system1). A large number of 4(3H)-quinazolinones, in particular those possessing 2-alkly-3-aryl2), 2,3-dialkyl3), and 2-alkyl-3-amino4) substitution, have been evaluated for pharmacological activity. On the other hand, thiazolidone derivatives are reported to have anesthetic5), anticonvulsant6), and hypnotic7) activity.