THE TREATMENT OF DISSEMINATED PROSTATE-CANCER WITH ESTRAMUSTINE

被引：1
|
作者：
ROSENTHAL, MA [1 ]
RAGHAVAN, D [1 ]
STUARTHARRIS, R [1 ]
ACKLAND, S [1 ]
GRYGIEL, J [1 ]
机构：
[1] ROYAL PRINCE ALFRED HOSP,UROL CANC RES UNIT,LEVEL E9,CAMPERDOWN,NSW 2050,AUSTRALIA
来源：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY | 1992年 / 62卷 / 11期
关键词：
ESTRAMUSTINE; PROSTATE CANCER;
D O I：
10.1111/j.1445-2197.1992.tb06942.x
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Forty-three patients with disseminated prostate cancer, resistant to orchidectomy or hormone therapy with estramustine were treated. Of the 33 evaluable patients, three patients had stable disease and two had a partial tumour response according to National Prostatic Cancer Project criteria. Twenty-five patients (58%) showed improvement in pain and urinary symptoms. Ten patients (23%) had side effects requiring cessation of therapy. These results show that estramustine has a limited role in the treatment of advanced prostate cancer and that therapy is frequently associated with intolerable side effects.
引用
收藏
页码：871 / 873
页数：3
相关论文
共 50 条
  • [1] INHIBITION OF PROSTATE-CANCER GROWTH BY ESTRAMUSTINE AND ETOPOSIDE
    PIENTA, KJ
    REDMAN, BG
    HUSSAIN, M
    ESPER, PS
    FLAHERTY, LE
    CANCER, 1995, 75 (07) : 1920 - 1926
  • [2] INHIBITION OF PROSTATE-CANCER GROWTH BY ESTRAMUSTINE AND COLCHICINE
    FAKIH, M
    YAGODA, A
    REPLOGLE, T
    LEHR, JE
    PIENTA, KJ
    PROSTATE, 1995, 26 (06) : 310 - 315
  • [3] CONTROVERSIES IN THE TREATMENT OF METASTATIC PROSTATE-CANCER
    MCLEOD, DG
    CRAWFORD, ED
    BLUMENSTEIN, BA
    EISENBERGER, MA
    DORR, FA
    CANCER, 1992, 70 (01) : 324 - 328
  • [4] LOCALIZED PROSTATE-CANCER - RELATIONSHIP OF TUMOR VOLUME TO CLINICAL-SIGNIFICANCE FOR TREATMENT OF PROSTATE-CANCER
    STAMEY, TA
    FREIHA, FS
    MCNEAL, JE
    REDWINE, EA
    WHITTEMORE, AS
    SCHMID, HP
    CANCER, 1993, 71 (03) : 933 - 938
  • [5] RECENT DEVELOPMENTS IN ENDOCRINE TREATMENT OF PROSTATE-CANCER
    VOGELZANG, NJ
    KENNEALEY, GT
    CANCER, 1992, 70 (04) : 966 - 976
  • [6] Evaluation of docetaxel plus estramustine in the treatment of patients with hormone-refractory prostate cancer
    Matsumoto, Akihiro
    Inoue, Atsushi
    Yokoi, Satoshi
    Nozumi, Kazuyoshi
    Miyazaki, Kanetaka
    Hosoki, Shigeru
    Nagata, Maki
    Yamaguchi, Kunio
    INTERNATIONAL JOURNAL OF UROLOGY, 2009, 16 (08) : 687 - 691
  • [7] GRADING PROSTATE-CANCER
    BOSTWICK, DG
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1994, 102 (04) : S38 - S56
  • [8] PATTERNS OF RADIATION TREATMENT OF ELDERLY PATIENTS WITH PROSTATE-CANCER
    HANKS, GE
    HANLON, A
    OWEN, JB
    SCHULTHEISS, TE
    CANCER, 1994, 74 (07) : 2174 - 2177
  • [9] Phase II trial of vinorelbine and estramustine in the treatment of metastatic hormone-resistant prostate cancer
    Borrega, P
    Velasco, A
    Bolaños, M
    Pérez, MD
    Mel, JR
    Reina, JJ
    Rodríguez-Jaraiz, MA
    Chaves, M
    González-Barón, M
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2004, 22 (01) : 32 - 35
  • [10] SCREENING FOR PROSTATE-CANCER
    CHODAK, GW
    EUROPEAN UROLOGY, 1993, 24 : 3 - 5
12345