BLEEDING AFTER TONSILLECTOMY IN SEVERE VON WILLEBRANDS DISEASE

被引:12
作者
ALUSI, GH
GRANT, WE
LEE, CA
PASI, KJ
PATH, MRC
STEARNS, MP
机构
[1] ROYAL FREE HOSP,SCH MED,CTR HAEMOPHILIA,LONDON NW3 2QG,ENGLAND
[2] ROYAL FREE HOSP,SCH MED,DEPT HAEMATOL,HAEMOSTASIS UNIT,LONDON NW3 2QG,ENGLAND
关键词
TONSILLECTOMY; HEMORRHAGE; VON WILLEBRANDS DISEASE; HIV;
D O I
10.1017/S0022215100130373
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
A case is reported of a HIV-positive patient with severe von Willebrand's disease describing the bleeding complications during and after tonsillectomy. This patient underwent surgery for asymmetrical tonsillar hypertrophy. The tonsils were spontaneously haemorrhaging and there therefore was a suspicion of neoplasia. Despite close cooperation between the ENT Department and the Haemophilia Centre, involving per-operative Factor VIII monitoring and replacement, the patient suffered both protracted primary and secondary haemorrhages. We report this as a cautionary tale as our previous experience with mild to moderate haemophilia has been uncomplicated, but on this occcasion there was massive haemorrhage. We feel that tonsillectomy should not be undertaken in a patient with a severe bleeding disorder without an absolute indicate.
引用
收藏
页码:437 / 439
页数:3
相关论文
共 9 条
[1]  
CASTILLO R, 1991, BLOOD, V77, P1991
[2]  
KHAIR K, 1994, 21 INT C WORLD FED H, P198
[3]   SURGERY IN HEMOPHILIA AND RELATED DISORDERS - A PROSPECTIVE-STUDY OF 100 CONSECUTIVE PROCEDURES [J].
KITCHENS, CS .
MEDICINE, 1986, 65 (01) :34-45
[4]   ABNORMALITIES OF B-CELL ACTIVATION AND IMMUNOREGULATION IN PATIENTS WITH THE ACQUIRED IMMUNODEFICIENCY SYNDROME [J].
LANE, HC ;
MASUR, H ;
EDGAR, LC ;
WHALEN, G ;
ROOK, AH ;
FAUCI, AS .
NEW ENGLAND JOURNAL OF MEDICINE, 1983, 309 (08) :453-458
[5]  
MANNUCCI PM, 1992, BLOOD, V79, P3130
[6]   CLINICAL AND LABORATORY EVALUATION OF THE TREATMENT OF VONWILLEBRANDS DISEASE PATIENTS WITH HEAT-TREATED FACTOR-VIII CONCENTRATE (BPL-8Y) [J].
PASI, KJ ;
WILLIAMS, MD ;
ENAYAT, MS ;
HILL, FGH .
BRITISH JOURNAL OF HAEMATOLOGY, 1990, 75 (02) :228-233
[7]  
PRINSLEY P, 1993, CLIN OTOLARYNGOL, V18, P206
[8]   THERAPY OF VONWILLEBRAND DISEASE [J].
SCOTT, JP ;
MONTGOMERY, RR .
SEMINARS IN THROMBOSIS AND HEMOSTASIS, 1993, 19 (01) :37-47
[9]  
1992, BLOOD COAGULATION FI, V3, P205