HYBRIDIZATION PROPERTIES OF THE 5-METHYL-ISOCYTIDINE ISOGUANOSINE BASE-PAIR IN SYNTHETIC OLIGODEOXYNUCLEOTIDES

被引：8
作者：
HORN, T
CHANG, CA
COLLINS, ML
机构：
[1] Nucleic Acids Systems, Chiron Corp., Emeryville
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
关键词：
D O I：
10.1080/15257779508012525
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The hybridization properties of the 5-methyl-isocytidine / isoguanosine base pair in synthetic oligodeoxynucleotides have been investigated. The 5-methyl-isocytidine / isoguanosine base pair has been determined to be isoenergetic with the cytidine / guanosine, and each base can effectively discriminate mismatches.
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页码：1023 / 1026
页数：4
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