DAY-TO-DAY VARIATION IN IRON-STATUS INDEXES IN HEALTHY-MEN AND WOMEN

被引：98

作者：

BOREL, MJ

SMITH, SM

DERR, J

BEARD, JL

机构：

[1] PENN STATE UNIV,DEPT NUTR,S-126 S HENDERSON BLDG,UNIVERSITY PK,PA 16802

[2] PENN STATE UNIV,DEPT STAT,UNIVERSITY PK,PA 16802

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1991年 / 54卷 / 04期

关键词：

IRON STATUS ASSESSMENT; PLASMA IRON; FERRITIN; HEMOGLOBIN; BIOLOGICAL VARIATION;

D O I：

10.1093/ajcn/54.4.729

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

We evaluated the day-to-day variation of four iron-status indices: hemoglobin (Hb), hematocrit (Hct), plasma ferritin (PF), and plasma iron (PI). Finger-prick blood samples were collected for 31 consecutive days in 20 healthy men and women. Replicate (sigma-rep2) and day-to-day (sigma-day2) variance components were estimated. Day-to-day variation in the iron-status measures was similar between men and women except for PF, for which the variation was greater in women. The CVs for a single future determination for Hb, Hct, PF, and PI were 4.6%, 3.0%, 15.2%, and 26.7% for males and 4.4%, 3.2%, 26.8%, and 29.0% for females, respectively. Three to 10 independent measurements are required to accurately determine PF and PI whereas one is adequate for Hb and Hct. Thus, day-to-day biological variation is a major component of the variability in these iron-status indicators and must be considered when assessing iron status.

引用

页码：729 / 735

页数：7

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