Acute viral hepatitis and liver failure

被引：0

作者：

Manka, P. ^{[1
]}

Jochum, C. ^{[1
]}

Timm, J. ^{[2
]}

Canbay, A. ^{[1
]}

机构：

[1] Univ Klinikum Essen, Klin Gastroenterol & Hepatol, Hufelandstr 55, D-45122 Essen, Germany

[2] Univ Klinikum Essen, Inst Virol, Essen, Germany

来源：

GASTROENTEROLOGE | 2013年 / 8卷 / 01期

关键词：

Hepatic Encephalopathy; Viral hepatitis; Hepatitis B reactivation; Atypical infections; Liver transplantation;

D O I：

10.1007/s11377-012-0688-4

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Viral hepatitis is one of the key causes for acute liver failure (ALF) worldwide. Although most cases related to acute viral hepatitis are asymptomatic or mild in the clinical presentation, a significant proportion end in fulminant liver failure leading to a high mortality. Acute infections with hepatitis A, B, D and E virus may lead to acute liver failure. In addition, other atypical infections can rarely cause ALF, whereas acute hepatitis C virus (HCV) virtually never causes ALF. Acute on chronic liver failure is generally associated with a poor prognosis. Reactivation of HBV infection under certain immunosuppressive conditions is an increasing problem. Liver transplantation represents the only therapeutic option for most virally induced cases of ALF.

引用

页码：7 / 13

页数：7

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