COMPLETE WATER SUPPRESSION FOR SOLUTIONS OF LARGE MOLECULES BASED ON DIFFUSIONAL DIFFERENCES BETWEEN SOLUTE AND SOLVENT (DRYCLEAN)

被引：89

作者：

VANZIJL, PCM ^{[1
]}

MOONEN, CTW ^{[1
]}

机构：

[1] NIH,DRS,BIOMED & INSTRUMENT BRANCH,BETHESDA,MD 20892

来源：

JOURNAL OF MAGNETIC RESONANCE | 1990年 / 87卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0022-2364(90)90082-K

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method is outlined for suppressing water in proton spectra using differences in its diffusion properties with the solutes. Solute protons at the water resonance frequency can be studied, the spectrum is not phase-distorted, and success of the technique does not depend on B1 homogeneity or water linewidth. No phase cycling is necessary and suppression is easier for larger solutes. © 1990.

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页码：18 / 25

页数：8

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