GOLD NANOPARTICLES-BASED BIOSENSORS FOR BIOMEDICAL APPLICATION

被引：6
作者：
Zhao, Jing [1 ]
Bo, Bing [2 ]
Yin, Yong-Mei [2 ]
Li, Gen-Xi [1 ,3 ,4 ]
机构：
[1] Shanghai Univ, Lab Biosensing Technol, Sch Life Sci, Shanghai 200444, Peoples R China
[2] Nanjing Med Univ, Affliated Hosp 1, Dept Oncol, Nanjing 210029, Jiangsu, Peoples R China
[3] Nanjing Univ, Dept Biochem, Nanjing 210093, Jiangsu, Peoples R China
[4] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Jiangsu, Peoples R China
来源：
NANO LIFE | 2012年 / 2卷 / 04期
关键词：
Gold nanoparticles; biosensor; biomedical application;
D O I：
10.1142/S1793984412300087
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Gold nanoparticles are the most extensively studied nanomaterials for biomedical application due to their unique properties, such as rapid and simple synthesis, large surface area, strong adsorption ability and facile conjugation to various biomolecules. The remarkable photophysical properties of gold nanoparticles have provided plenty of opportunities for the preparation of gold nanoparticles- based optical biosensors, while the excellent biocompatibility, conductivity, catalytic properties and large surface-to-volume ratio have facilitated the application of gold nanoparticles in the construction of electrochemical biosensors. In this review, we mainly detail the gold nanoparticles-based optical and electrochemical biosensors for biomedical application in the recent two years, which have exhibited greatly enhanced analytical performances in the detection of DNA, proteins and some important small molecules.
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页数：11
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