A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

被引：13

作者：

Cox, Elaine G. ^{[1
]}

Knoderer, Chad A. ^{[1
,2
]}

Jennings, Aimee ^{[3
]}

Brown, John W. ^{[4
]}

Rodefeld, Mark D. ^{[4
]}

Walker, Scott G. ^{[5
]}

Turrentine, Mark W.

机构：

[1] Indiana Univ, Sch Med, Sect Pediat Infect Dis, Bloomington, IN 47405 USA

[2] Butler Univ, Coll Pharm & Hlth Sci, Dept Pharm Practice, Indianapolis, IN 46208 USA

[3] Indiana Univ, Sch Med, Dept Nursing, Indianapolis, IN 47405 USA

[4] Indiana Univ, Sch Med, Div Cardiothorac Surg, Indianapolis, IN 47405 USA

[5] Indiana Univ, Sch Med, Dept Anesthesia, Indianapolis, IN 47405 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2013年 / 2卷 / 01期

关键词：

D O I：

10.1093/jpids/pis066

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We conducted a randomized, controlled clinical trial to determine whether a difference in catheter-associated blood stream infection (CABSI) incidence existed between children who underwent cardiac surgery and had a central venous catheter impregnated with minocycline and rifampin versus those who had a conventional, nonimpregnated catheter after cardiac surgery. Due to a lower number of infections than expected, the study was terminated early. Among 288 evaluable patients, the rates of CABSI and line-related complications were similar between the 2 groups.

引用

页码：67 / 70

页数：4

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