A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

被引:13
作者
Cox, Elaine G. [1 ]
Knoderer, Chad A. [1 ,2 ]
Jennings, Aimee [3 ]
Brown, John W. [4 ]
Rodefeld, Mark D. [4 ]
Walker, Scott G. [5 ]
Turrentine, Mark W.
机构
[1] Indiana Univ, Sch Med, Sect Pediat Infect Dis, Bloomington, IN 47405 USA
[2] Butler Univ, Coll Pharm & Hlth Sci, Dept Pharm Practice, Indianapolis, IN 46208 USA
[3] Indiana Univ, Sch Med, Dept Nursing, Indianapolis, IN 47405 USA
[4] Indiana Univ, Sch Med, Div Cardiothorac Surg, Indianapolis, IN 47405 USA
[5] Indiana Univ, Sch Med, Dept Anesthesia, Indianapolis, IN 47405 USA
关键词
D O I
10.1093/jpids/pis066
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We conducted a randomized, controlled clinical trial to determine whether a difference in catheter-associated blood stream infection (CABSI) incidence existed between children who underwent cardiac surgery and had a central venous catheter impregnated with minocycline and rifampin versus those who had a conventional, nonimpregnated catheter after cardiac surgery. Due to a lower number of infections than expected, the study was terminated early. Among 288 evaluable patients, the rates of CABSI and line-related complications were similar between the 2 groups.
引用
收藏
页码:67 / 70
页数:4
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