Phosphorylation at endothelial cell-cell junctions: Implications for VE-cadherin function

被引：0

作者：

Timmerman, Ilse ^{[1
]}

Hordijk, Peter L. ^{[1
]}

van Buul, Jaap D. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Mol Cell Biol, Sanquin Res & Landsteiner Lab, Amsterdam, Netherlands

来源：

CELL HEALTH AND CYTOSKELETON | 2010年 / 2卷

关键词：

endothelium; VE-cadherin; junctions; barrier; phosphorylation;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Endothelial cell-cell junctions are strictly regulated in order to control the barrier function of endothelium. Vascular endothelial (VE)-cadherin is one of the proteins that is crucial in this process. It has been reported that phosphorylation events control the function of VE-cadherin. This review summarizes the role of VE-cadherin phosphorylation in the regulation of endothelial cell-cell junctions and highlights how this affects vascular permeability and leukocyte extravasation.

引用

页码：23 / 31

页数：9

共 72 条

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