EARLY ONSET AND ACCUMULATION OF REM-SLEEP IN DEPRESSION - A STUDY OF THE PHASE-ADVANCE HYPOTHESIS

被引:4
作者
ZAMMIT, GK
POLLAK, C
ROSENBAUM, AH
ROTH, T
机构
[1] Department of Psychiatry, The St. Luke's/Roosevelt Hospital Center, NY
[2] Institute of Chronobiology, Cornell University Medical College, White Plains, NY
[3] Department of Psychiatry, McAuley Hospital, Ann Arbor, MI
[4] Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI
关键词
Chronobiology; Key words-Depression; Phase-advance; REM sleep;
D O I
10.3109/07420529009056968
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
-Twenty-two depressed subjects who met criteria for major depressive disorder were grouped according to their initial REM latency. Subjects with short (≥ 60 min) initial REM latency were separated from those with normal (< 60 min) initial REM latency. Subjects with short initial REM latency were found to have earlier onsets to at least two subsequent REM periods. The number of minutes of REM sleep accumulated were also plotted against elapsed time after sleep onset. The short-latency group accumulated REM sleep earlier than, but at about the same rate as, the normal latency group. These data support the phase-advance hypothesis of REM sleep in depression. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:165 / 169
页数:5
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