CIRCULATORY AND CELLULAR IMMUNE-RESPONSES TO SQUAMOUS-CELL CARCINOMA OF UTERINE CERVIX

被引：23
作者：
CHIANG, WT
WEI, PY
ALEXANDER, ER
机构：
[1] UNIV WASHINGTON, SCH PUBL HLTH & COMMUNITY MED, DEPT EPIDEMIOL & INT HLTH, SEATTLE, WA 98195 USA
[2] NATL TAIWAN UNIV, SCH MED, DEPT OBSTET & GYNECOL, TAIPEI, TAIWAN
[3] NATL TAIWAN UNIV HOSP, TAIPEI, TAIWAN
来源：
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1976年 / 126卷 / 01期
关键词：
D O I：
10.1016/0002-9378(76)90475-0
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The sera from 176 patients with cervical cancer were examined by indirect immunofluorescence against cervical cancer cells (imprints of cervical cancer tissue). The mean serum titer in these patients was significantly higher than the titer in 2 control groups of identical size. These tumor-related antibodies were also higher in titer in sera from a small sample of 9 husbands of cancer patients than in 18 control group patients. A cell mediated immune response was studied with the use of leukocyte migration inhibition from 39 blood specimens, including 23 patients with invasive epithelial carcinoma, 5 with intraepithelial carcinoma of the uterine cervix, 6 with other gynecologic disease and 5 without gynecologic disease. Migration inhibition was demonstrated for squamous cell carcinoma of the uterine cervix, suggesting a common specific cell-mediated response.
引用
收藏
页码：116 / 121
页数：6
相关论文
共 13 条
[1]  
BLOOM BR, 1969, ELABORATION EFFECTOR, P247
[2]   CELLULAR-HYPERSENSITIVITY IN PATIENTS WITH SQUAMOUS-CELL CARCINOMA OF CERVIX [J].
CHEN, SS ;
KOFFLER, D ;
COHEN, CJ .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1975, 121 (01) :91-95
[3]   CELL-MEDIATED IMMUNITY TO HUMAN MALIGNANT CELLS - BRIEF REVIEW AND FURTHER STUDIES WITH 2 GYNECOLOGIC TUMORS [J].
DISAIA, PJ ;
RUTLEDGE, FN ;
SMITH, JP ;
SINKOVICS, JG .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1972, 114 (07) :979-+
[4]   CELLULAR IMMUNITY AS A HOST RESPONSE TO SQUAMOUS CARCINOMA OF CERVIX [J].
GOLDSTEIN, MS ;
SHORE, B ;
GUSBERG, SB .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1971, 111 (06) :751-+
[5]   DEMONSTRATION OF CELL-BOUND AND HUMORAL IMMUNITY AGAINST NEUROBLASTOMA CELLS [J].
HELLSTROM, IE ;
HELLSTROM, KE ;
PIERCE, GE ;
BILL, AH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 60 (04) :1231-+
[6]   VALUE OF ASSAY OF CHROMOSOMES IN DIAGNOSIS OF CERVICAL NEOPLASIA [J].
JONES, HW ;
DAVIS, HJ ;
FROST, JK ;
PARK, IJ ;
SALIMI, R ;
TSENG, PY ;
WOODRUFF, JD .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1968, 102 (05) :624-&
[7]  
KLEIN G, 1967, JNCI-J NATL CANCER I, V39, P1027
[8]   TUMOUR-SPECIFIC ANTIBODIES IN HUMAN MALIGNANT MELANOMA AND THEIR RELATIONSHIP TO EXTENT OF DISEASE [J].
LEWIS, MG ;
IKONOPISOV, RL ;
NAIRN, RC ;
PHILLIPS, TM ;
FAIRLEY, GH ;
BODENHAM, DC ;
ALEXANDER, P .
BMJ-BRITISH MEDICAL JOURNAL, 1969, 3 (5670) :547-+
[9]  
MORTON DL, 1968, SURGERY, V64, P233
[10]   PRECIPITATING ANTIBODY IN HUMAN SERUM TO AN ANTIGEN PRESENT IN CULTURED BURKITTS LYMPHOMA CELLS [J].
OLD, LJ ;
BOYSE, EA ;
OETTGEN, HF ;
DEHARVEN, E ;
GEERING, G ;
WILLIAMSON, B ;
CLIFFORD, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 56 (06) :1699-+
12