THE CYTODIAGNOSIS OF MENINGEAL INVOLVEMENT IN FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

被引：0
作者：
WEHLE, K
GOBEL, U
PFITZER, P
机构：
[1] HEINRICH HEINE UNIV DUSSELDORF,DIV CYTOPATHOL,MOORENSTR 5,W-4000 DUSSELDORF 1,GERMANY
[2] HEINRICH HEINE UNIV,INST CYTOPATHOL,DUSSELDORF,GERMANY
[3] HEINRICH HEINE UNIV,PAEDIAT ONCOL CLIN,DUSSELDORF,GERMANY
来源：
CYTOPATHOLOGY | 1995年 / 6卷 / 01期
关键词：
FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; ERYTHROPHAGOCYTOSIS; RETICULOENDOTHELIOSIS; CSF CYTOLOGY; HISTIOCYTOSIS;
D O I：
10.1111/j.1365-2303.1995.tb00005.x
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The cytological appearances of the cerebrospinal fluid (CSF) in two cases of familial haemophagocytic lymphohistiocytosis (FHL) are described. The presence of numerous lymphocytes and immature macrophages in the CSF, some of which showed lymphohistiocytosis, was indicative of meningeal involvement. The appearance of large numbers of immature macrophages indicated rapid deterioration and death within a few weeks. Furthermore, some CSF samples taken at times when the patients were asymptomatic contained suspicious cells, indicating asymptomatic persistence of the meningeal lesions. Thus, cytological examination of CSF can assist with the management of patients with this rare disease.
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页码：30 / 38
页数：9
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