ADENOVIRUS AND ADENOASSOCIATED VIRUS-MEDIATED GENE-TRANSFER

被引：102
作者：
KREMER, EJ
PERRICAUDET, M
机构：
[1] Lab. de Genetique de Virus Oncogenes, Institut Gustave Roussy, Villejuif
来源：
BRITISH MEDICAL BULLETIN | 1995年 / 51卷 / 01期
关键词：
D O I：
10.1093/oxfordjournals.bmb.a072951
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this review we describe current strategies for adenoviral mediated gene transfer (AMGT) and adeno-associated viral mediated gene transfer (AAVMGT). We consider the structure and molecular biology of adenoviruses and adeno-associated viruses and detail the current advantages and disadvantages of AMGT and AAVMGT. Potential solutions to some of the specific drawbacks to AMGT, including the development of new vectors, addition of gp19k, organoides, and the use of non-human adenoviral vectors, are discussed.
引用
收藏
页码：31 / 44
页数：14
相关论文
共 34 条
  • [1] TRANSFER OF A FOREIGN GENE INTO THE BRAIN USING ADENOVIRUS VECTORS
    AKLI, S
    CAILLAUD, C
    VIGNE, E
    STRATFORDPERRICAUDET, LD
    POENARU, L
    PERRICAUDET, M
    KAHN, A
    PESCHANSKI, MR
    [J]. NATURE GENETICS, 1993, 3 (03) : 224 - 228
  • [2] ADENOVIRUS - TRANSFORMATION AND ONCOGENICITY
    BERNARDS, R
    VANDEREB, AJ
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 783 (03) : 187 - 204
  • [3] PARVOVIRUS REPLICATION
    BERNS, KI
    [J]. MICROBIOLOGICAL REVIEWS, 1990, 54 (03) : 316 - 329
  • [4] PACKAGING CAPACITY AND STABILITY OF HUMAN ADENOVIRUS TYPE-5 VECTORS
    BETT, AJ
    PREVEC, L
    GRAHAM, FL
    [J]. JOURNAL OF VIROLOGY, 1993, 67 (10) : 5911 - 5921
  • [5] HIGH-EFFICIENCY RECEPTOR-MEDIATED DELIVERY OF SMALL AND LARGE (48 KILOBASE GENE CONSTRUCTS USING THE ENDOSOME-DISRUPTION ACTIVITY OF DEFECTIVE OR CHEMICALLY INACTIVATED ADENOVIRUS PARTICLES
    COTTEN, M
    WAGNER, E
    ZATLOUKAL, K
    PHILLIPS, S
    CURIEL, DT
    BIRNSTIEL, ML
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (13) : 6094 - 6098
  • [6] Doerfler W, 1993, EXS, V64, P262
  • [7] A PROPOSED TERMINOLGY FOR ADENOVIRUS ANTIGENS AND VIRION MORPHOLOGICAL SUBUNITS
    GINSBERG, HS
    PEREIRA, HG
    VALENTINE, RC
    WILCOX, WC
    [J]. VIROLOGY, 1966, 28 (04) : 782 - +
  • [8] THE 10,400-DALTON AND 14,500-DALTON PROTEINS ENCODED BY REGION E3 OF ADENOVIRUS FUNCTION TOGETHER TO PROTECT MANY BUT NOT ALL MOUSE-CELL LINES AGAINST LYSIS BY TUMOR-NECROSIS-FACTOR
    GOODING, LR
    RANHEIM, TS
    TOLLEFSON, AE
    AQUINO, L
    DUERKSENHUGHES, P
    HORTON, TM
    WOLD, WSM
    [J]. JOURNAL OF VIROLOGY, 1991, 65 (08) : 4114 - 4123
  • [9] STEPWISE DISMANTLING OF ADENOVIRUS-2 DURING ENTRY INTO CELLS
    GREBER, UF
    WILLETTS, M
    WEBSTER, P
    HELENIUS, A
    [J]. CELL, 1993, 75 (03) : 477 - 486
  • [10] HADDADA H, 1994, CURR TOP MICROBIOL I
1234