RESPIRATORY-TRACT COLONIZATION WITH UREAPLASMA-UREALYTICUM AND BRONCHOPULMONARY DYSPLASIA IN NEONATES IN SOUTHERN ISRAEL

被引：29

作者：

HOROWITZ, S ^{[1
]}

LANDAU, D ^{[1
]}

SHINWELL, ES ^{[1
]}

ZMORA, E ^{[1
]}

DAGAN, R ^{[1
]}

机构：

[1] BEN GURION UNIV NEGEV,SOROKA UNIV MED CTR,FAC HLTH SCI,PEDIAT INFECT DIS UNIT,IL-84105 BEER SHEVA,ISRAEL

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 1992年 / 11卷 / 10期

关键词：

UREAPLASMA-UREALYTICUM; PREMATURE NEONATES; NASOPHARYNGEAL AND ENDOTRACHEAL CULTURES; BRONCHOPULMONARY DYSPLASIA;

D O I：

10.1097/00006454-199210000-00008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ureaplasma urealyticum has been recognized as an important potential pathogen in premature neonates. Reported rates of colonization of the respiratory tract vary. Data on neonatal ureaplasma colonization outside the United States and Western Europe are rare. Therefore we prospectively studied nasopharyngeal and endotracheal colonization in a cohort of 114 preterm and 100 full term infants within 48 hours of birth. The colonization rate was 24% in the premature infants and zero in the full term infants. Bronchopulmonary dysplasia developed in 19% of infants with nasopharyngeal Ureaplasma colonization and in 4.6% of noncolonized infants (P < 0.03). Bronchopulmonary dysplasia developed in 40% of intubated infants with positive endotracheal Ureaplasma cultures and only in 9.8% of infants with negative endotracheal cultures (P < 0.04). Thus Ureaplasma colonization of either the nasopharynx or the trachea was associated with an increased risk for the development of bronchopulmonary dysplasia (relative risk, 4.0 and 4.1, respectively).

引用

页码：847 / 851

页数：5

共 28 条

[1]

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[2]

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