Lifestyle Modifications and Colorectal Cancer

被引:104
作者
Durko, Lukasz [1 ]
Malecka-Panas, Ewa [1 ]
机构
[1] Med Univ Lodz, Dept Digest Tract Dis, Kopcinskiego 22, PL-90153 Lodz, Poland
关键词
Colorectal cancer; Prevention; Lifestyle modification; Phytochemicals; Obesity; Physical activity;
D O I
10.1007/s11888-013-0203-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Many studies suggest that Western lifestyle and dietary factors may be responsible for the high incidence of colorectal cancer in industrialized countries. Consumption of high amounts of red and processed meat and low intake of fiber and multiple protective phytochemicals found in fruits, vegetables, and whole grainsmight be responsible for the high incidence of this neoplasmin theWesternworld. Additionally, obesity, lack of physical activity, tobacco and alcohol use, sleep deprivation, and other factors have been proven to further increase the risk of colorectal cancer. Identifying and understanding the mechanisms through which they impact colon carcinogenesis is needed for the introduction of protective lifestyle recommendations.
引用
收藏
页码:45 / 54
页数:10
相关论文
共 100 条
[1]   Lipid oversupply, selective insulin resistance, and lipotoxicity: Molecular mechanisms [J].
Antonio Chavez, Jose ;
Summers, Scott A. .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2010, 1801 (03) :252-265
[2]  
Aroch Ilan, 2010, Therap Adv Gastroenterol, V3, P281, DOI 10.1177/1756283X10379258
[3]   Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota [J].
Arthur, Janelle C. ;
Perez-Chanona, Ernesto ;
Muehlbauer, Marcus ;
Tomkovich, Sarah ;
Uronis, Joshua M. ;
Fan, Ting-Jia ;
Campbell, Barry J. ;
Abujamel, Turki ;
Dogan, Belgin ;
Rogers, Arlin B. ;
Rhodes, Jonathan M. ;
Stintzi, Alain ;
Simpson, Kenneth W. ;
Hansen, Jonathan J. ;
Keku, Temitope O. ;
Fodor, Anthony A. ;
Jobin, Christian .
SCIENCE, 2012, 338 (6103) :120-123
[4]   Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats [J].
Asghar, Mohammad ;
George, Liza ;
Lokhandwala, Mustafa F. .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2007, 293 (03) :F914-F919
[5]   Non-digestible fraction of cooked bean (Phaseolus vulgaris L.) cultivar Bayo Madero suppresses colonic aberrant crypt foci in azoxymethane-induced rats [J].
Azeneth Vergara-Castaneda, Hayde ;
Gerardo Guevara-Gonzalez, Ramon ;
Ramos-Gomez, Minerva ;
Reynoso-Camacho, Rosalia ;
Guzman-Maldonado, Horacio ;
Angelica Feregrino-Perez, Ana ;
Oomah, B. Dave ;
Loarca-Pina, Guadalupe .
FOOD & FUNCTION, 2010, 1 (03) :294-300
[6]   The contribution of animal fat oxidation products to colon carcinogenesis, through modulation of TGF-β1 signaling [J].
Biasi, Fiorella ;
Mascia, Cinzia ;
Poli, Giuseppe .
CARCINOGENESIS, 2008, 29 (05) :890-894
[7]   Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study [J].
Bingham, SA ;
Day, NE ;
Luben, R ;
Ferrari, P ;
Slimani, N ;
Norat, T ;
Clavel-Chapelon, F ;
Kesse, E ;
Nieters, A ;
Boeing, H ;
Tjonneland, A ;
Overvad, K ;
Martinez, C ;
Dorronsoro, M ;
Gonzalez, CA ;
Key, TJ ;
Trichopoulou, A ;
Naska, A ;
Vineis, P ;
Tumino, R ;
Krogh, V ;
Bueno-de-Mesquita, HB ;
Peeters, PHM ;
Berglund, G ;
Hallmans, G ;
Lund, E ;
Skeie, G ;
Kaaks, R ;
Riboli, E .
LANCET, 2003, 361 (9368) :1496-1501
[8]   In vitro genotoxicity of ethanol and acetaldehyde in human lymphocytes and the gastrointestinal tract mucosa cells [J].
Blasiak, J ;
Trzeciak, A ;
Malecka-Panas, E ;
Drzewoski, J ;
Wojewódzka, M .
TOXICOLOGY IN VITRO, 2000, 14 (04) :287-295
[9]   DNA damage in human colonic mucosa cells evoked by nickel and protective action of quercetin - Involvement of free radicals? [J].
Blasiak, J ;
Arabski, M ;
Pertynski, T ;
Malecka-Panas, E ;
Wozniak, K ;
Drzewoski, J .
CELL BIOLOGY AND TOXICOLOGY, 2002, 18 (04) :279-288
[10]   Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy [J].
Booth, FW ;
Chakravarthy, MV ;
Gordon, SE ;
Spangenburg, EE .
JOURNAL OF APPLIED PHYSIOLOGY, 2002, 93 (01) :3-30