Polytolypin, a new antifungal triterpenoid from the coprophilous fungus Polytolypa hystricis

被引:14
作者
Gamble, WR
Gloer, JB
Scott, JA
Malloch, D
机构
[1] UNIV IOWA,DEPT CHEM,IOWA CITY,IA 52242
[2] UNIV TORONTO,DEPT BOT,TORONTO,ON M5S 1A1,CANADA
来源
JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 12期
关键词
D O I
10.1021/np50126a034
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Polytolypin [1], a new pentacyclic triterpenoid exhibiting antifungal and antibiotic activity, has been isolated from cultures of Polytolypa hystricis (JS189), a fungal colonist of porcupine dung. Two known compounds [2 and 3] were also isolated. Polytolypin was obtained by chromatographic fractionation of the EtOAc extract of P. hystricis liquid cultures, and the structure was assigned on the basis of 2D nmr and hrms data.
引用
收藏
页码:1983 / 1986
页数:4
相关论文
共 9 条
[1]  
AHMAD VU, 1994, HDB NATURAL PRODUCTS, V2, P1346
[2]   APIOSPORAMIDE, A NEW ANTIFUNGAL AGENT FROM THE COPROPHILOUS FUNGUS APIOSPORA-MONTAGNEI [J].
ALFATAFTA, AA ;
GLOER, JB ;
SCOTT, JA ;
MALLOCH, D .
JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1994, 57 (12) :1696-1702
[3]   METABOLITES PRODUCED BY THE SCLERODERRIS CANKER FUNGUS, GREMMENIELLA-ABIETINA .1. [J].
AYER, WA ;
HOYANO, Y ;
PEDRAS, MS ;
VANALTENA, I .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1986, 64 (08) :1585-1589
[4]   THE CHEMISTRY OF FUNGAL ANTAGONISM AND DEFENSE [J].
GLOER, JB .
CANADIAN JOURNAL OF BOTANY-REVUE CANADIENNE DE BOTANIQUE, 1995, 73 :S1265-S1274
[5]   INTERFERENCE COMPETITION AMONG COPROPHILOUS FUNGI - PRODUCTION OF (+)-ISOEPOXYDON BY PORONIA-PUNCTATA [J].
GLOER, JB ;
TRUCKENBROD, SM .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1988, 54 (04) :861-864
[6]   POLYTOLYPA, AN UNDESCRIBED GENUS IN THE ONYGENALES [J].
SCOTT, JA ;
MALLOCH, DW ;
GLOER, JB .
MYCOLOGIA, 1993, 85 (03) :503-508
[7]   STRUCTURES OF RETIGERIC ACIDS A AND B FROM LICHENS OF LOBARIA-RETIGERA GROUP [J].
TAKAHASHI, R ;
TANAKA, O ;
CHIANG, HC ;
AIMI, N .
PHYTOCHEMISTRY, 1972, 11 (06) :2039-+
[8]  
TURNER WB, 1971, FUNGAL METABOLITES, P263
[9]  
TURNER WB, 1983, FUNGAL METABOLITES, V2, P325