RACIAL-DIFFERENCES IN THE ASSOCIATION BETWEEN MATERNAL SMOKING DURING PREGNANCY AND LUNG-FUNCTION IN CHILDREN

被引:35
作者
CUNNINGHAM, J
DOCKERY, DW
GOLD, DR
SPEIZER, FE
机构
[1] HARVARD UNIV, SCH PUBL HLTH, DEPT ENVIRONM HLTH, ENVIRONM EPIDEMIOL PROGRAM, BOSTON, MA 02115 USA
[2] HARVARD UNIV, SCH PUBL HLTH, DEPT EPIDEMIOL, BOSTON, MA 02115 USA
[3] HARVARD UNIV, BETH ISRAEL HOSP, SCH MED, DEPT MED, CHANNING LAB, BOSTON, MA USA
关键词
D O I
10.1164/ajrccm.152.2.7633708
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
We recently reported that suburban white schoolchildren whose mothers smoked during pregnancy have significantly reduced lung function. Because inner-city and minority children may be at greater risk for respiratory morbidity, we evaluated the relationship between maternal smoking during pregnancy and lung function in 493 white and 383 black schoolchildren 9 to 11 yr of age in three areas of Philadelphia. The child's passive smoking history was determined from reports by the mother. Spirometry was performed at school. After adjusting for height, weight, age, sex, area of city, race, socioeconomic status, and current exposure to environmental tobacco smoke at home, maternal smoking during pregnancy was associated with significant deficits in FEF(25-75) (-8.1%) and FEV(1)/FVC (-2.0%). The observed deficits were larger for black children than for white children, and they were larger for boys than for girls. These results provide additional evidence of an association between maternal smoking during pregnancy and reduced pulmonary function in children, and they suggest that the association may be modified by race and/or sex.
引用
收藏
页码:565 / 569
页数:5
相关论文
共 17 条
[1]  
CHARNOCK EL, 1973, PEDIATR CLIN N AM, V20, P275
[2]   MATERNAL SMOKING DURING PREGNANCY AS A PREDICTOR OF LUNG-FUNCTION IN CHILDREN [J].
CUNNINGHAM, J ;
DOCKERY, DW ;
SPEIZER, FE .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 139 (12) :1139-1152
[3]  
EISEN EA, 1985, AM REV RESPIR DIS, V132, P120
[4]   THE ASSOCIATION BETWEEN HEALTH-STATUS AND THE PERFORMANCE OF EXCESSIVELY VARIABLE SPIROMETRY TESTS IN A POPULATION-BASED STUDY IN 6 UNITED-STATES CITIES [J].
EISEN, EA ;
DOCKERY, DW ;
SPEIZER, FE ;
FAY, ME ;
FERRIS, BG .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1987, 136 (06) :1371-1376
[5]   RACE AND GENDER DIFFERENCES IN RESPIRATORY ILLNESS PREVALENCE AND THEIR RELATIONSHIP TO ENVIRONMENTAL EXPOSURES IN CHILDREN 7 TO 14 YEARS OF AGE [J].
GOLD, DR ;
ROTNITZKY, A ;
DAMOKOSH, AI ;
WARE, JH ;
SPEIZER, FE ;
FERRIS, BG ;
DOCKERY, DW .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 148 (01) :10-18
[6]   THE EFFECT OF MATERNAL SMOKING DURING PREGNANCY ON EARLY INFANT LUNG-FUNCTION [J].
HANRAHAN, JP ;
TAGER, IB ;
SEGAL, MR ;
TOSTESON, TD ;
CASTILE, RG ;
VANVUNAKIS, H ;
WEISS, ST ;
SPEIZER, FE .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1992, 145 (05) :1129-1135
[7]   TRACKING OF LUNG-FUNCTION IN HEALTHY-CHILDREN AND ADOLESCENTS [J].
HIBBERT, ME ;
HUDSON, IL ;
LANIGAN, A ;
LANDAU, LI ;
PHELAN, PD .
PEDIATRIC PULMONOLOGY, 1990, 8 (03) :172-177
[8]   CONCENTRATION OF INDOOR PARTICULATE MATTER AS A DETERMINANT OF RESPIRATORY HEALTH IN CHILDREN [J].
NEAS, LM ;
DOCKERY, DW ;
WARE, JH ;
SPENGLER, JD ;
FERRIS, BG ;
SPEIZER, FE .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 139 (11) :1088-1099
[9]  
POLGAR G, 1979, AM REV RESPIR DIS, V120, P625
[10]   PREDICTORS OF ASTHMA AND PERSISTENT WHEEZE IN A NATIONAL SAMPLE OF CHILDREN IN THE UNITED-STATES - ASSOCIATION WITH SOCIAL-CLASS, PERINATAL EVENTS, AND RACE [J].
SCHWARTZ, J ;
GOLD, D ;
DOCKERY, DW ;
WEISS, ST ;
SPEIZER, FE .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1990, 142 (03) :555-562